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24 results found

Old dogs

3 April 2023 |
It is always nice to get a thank you card, especially so when it comes from someone at the tail end of an overbooked clinic who had waited patiently well past their appointed slot. Such was the case when I...

Review of pathogenesis of Acanthamoeba keratitis

4 February 2021 | | Cornea / External Eye Disease | Acanthamoeba, Contact lens, Cornea, Immunology, Keratitis, Microbiome, Pathology
In this review, the author summarised the current microbiomic and immunological evidence related to the pathogenesis of Acanthamoeba keratitis (AK). AK has been described for almost 50 years, but the exact biology of the disease remains perplexing. Acanthamoeba spp. are...

Cutting-edge practice in glaucoma care: what, how and why?

1 April 2016 | | Glaucoma
More effective treatments and drug delivery modalities, implantable minimally invasive glaucoma surgical (MIGS) devices, as well as accelerating clinical research programmes, will transform the surgical and clinical management of glaucoma in the near future. There is also an ever-greater emphasis...

Coeliac disease and anterior scleritis

1 February 2014 | | Paediatric Ophthalmology / Strabismus
The authors present an interesting case report of recurrent anterior scleritis. Circulating IgA and IgG auto-antibodies directed against tissue transglutaminase, endomisium and gliadin are frequently elevated in patients with coeliac disease. The classic symptoms remain chronic diarrhoea, malabsorption syndromes and...

Paraproteinaemia: a patient with atypical corneal findings

1 December 2013 | | Ophthalmology, Cornea / External Eye Disease
A Bence Jones protein is a monoclonal globulin protein or immunoglobulin light chain found in the urine, with a molecular weight of 22-24 kDa [1]. Detection of Bence Jones protein may be suggestive of multiple myeloma or Waldenström’s macroglobulinemia. Multiple...

Blurred vision post liver transplant: to blame the house cat or not?

1 October 2014 | | AMD, Cataract and Refractive, Cornea / External Eye Disease, Emergency Ophthalmology, Genetics, Glaucoma, Imaging, Neuro-Ophthalmology, Ocular Pathology and Oncology, Oculoplastics, Ophthalmology, Optometry, Orbit, Paediatric Ophthalmology / Strabismus, Retina / Uvea / Vitreous
This article outlines a case of atypical ocular toxoplasmosis associated with immunosuppression. There were two potential sources of infection in this patient and we describe how we concluded which was the most likely. Case report A 33-year-old female was referred...

Acute retinal necrosis presumably caused by Epstein-Barr virus infection

1 October 2015 | | AMD, Cataract and Refractive, Cornea / External Eye Disease, Emergency Ophthalmology, Genetics, Glaucoma, Imaging, Neuro-Ophthalmology, Ocular Pathology and Oncology, Oculoplastics, Ophthalmology, Optometry, Orbit, Paediatric Ophthalmology / Strabismus, Retina / Uvea / Vitreous
Acute retinal necrosis (ARN) is an uncommon, but serious and potentially blinding condition. ARN is characterised by panuveitis, occlusive vasculopathy and progressive peripheral necrotising retinitis. The diagnosis is clinical but confirmation is sought via aqueous and vitreous sampling. Varicella zoster...

Friendly felines and a spot diagnosis

1 June 2014 | | Retina / Uvea / Vitreous
A nine-year-old girl presented to me in eye casualty with a three-week history of blurred vision in her left eye. Otherwise she was apparently well, with no past ophthalmic, medical, drug or relevant family history. Visual acuity was 6/4 right...

Ocular mucous membrane pemphigoid: the importance of early detection and treatment

1 August 2014 | | Oculoplastics, Orbit
Mucous membrane pemphigoid (MMP) is an autoimmune blistering disorder that is characterised by subepithelial bullae. The ocular manifestation of MMP, ocular mucous membrane pemphigoid (OMMP), is a sight-threatening condition characterised by conjunctival cicatricial changes associated with corneal vascularisation and scarring....

Unilateral central scotoma following dengue fever

12 October 2023 | | Neuro-Ophthalmology, ONLINE EXCLUSIVE ARTICLES
Case report A 16-year-old Caucasian male was referred to the eye casualty at Nottingham University Hospitals NHS Trust by the infectious diseases unit in September 2013. He gave a history of photophobia, pain on eye movements and central blurred vision...

Toxoplasmosis and the associated retinochoroiditis: important facts and when to treat

1 April 2017 | | Retina / Uvea / Vitreous
Annie SeeWah Tung provides an overview of toxoplasmosis retinochoroiditis, including guidance on which cases should be treated and the treatment options. Toxoplasmosis retinochoroiditis is an infectious condition that is characterised by retinochoroidal lesions commonly in the posterior pole and is...

The paediatric cataract: an overview of the embryology and pathophysiology

5 February 2020 | | Ophthalmology, Paediatric Ophthalmology / Strabismus, Cataract and Refractive
In the first of the two articles (see Part 2 here) on paediatric cataracts, Samuel Aryee reviews the aetiology of this condition. Cataracts arise from opacification of the natural transparent lens, which can cause partial or total blindness. Although the...
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