You searched for "atrophy"
The natural history of treatment naïve choroidal neovascularisation (CNV) in geographic atrophy
1 February 2018
| Efrosini Papagiannuli
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EYE - Vitreo-Retinal
The aim of this retrospective study is to assess the characteristics and natural history of quiescent CNV in geographic atrophy (GA) utilising multi-modal imaging. Case notes were reviewed of patients diagnosed with geographic atrophy between January 2010 and December 2016...
Bosch-Boonstro-Schaaff optic atrophy syndrome (BBSOAS) NR2F1 mutation
4 December 2023
| Soman Raman, Neda Qurashi, Qasim Mansoor
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EYE - Neuro-ophthalmology
An experienced ophthalmologist can make an anatomical diagnosis of childhood visual impairment based upon the surgical sieve, i.e., congenital and acquired. But an ophthalmologist cannot work in isolation to make an aetiological diagnosis – one would require the help of...
Emerging therapies for geographic atrophy: complement inhibitors show potential to slow progression and preserve RPE and photoreceptor integrity
5 June 2023
| Rod McNeil
Geographic atrophy (GA) is an advanced form of age-related macular degeneration (AMD) characterised by progressive, irreversible loss of the retinal pigment epithelium (RPE) and photoreceptors and is estimated to account for approximately 10% of AMD-related blindness [1-4]. The Age-Related Eye...
AI breakthrough brings geographic atrophy treatment a step closer
20 September 2021
A team led by Dr Konstantinos Balaskas at Moorfields Eye Hospital Reading Centre has developed a fully automated, deep-learning model (algorithm) that can detect and quantify geographic atrophy using standard optical coherence tomography (OCT) scans.
PREVIEW: Join us at the TROPHY Ophthalmic Conference 2025!
The highly anticipated TROPHY Ophthalmic Conference returns this year with an impressive lineup of experts, cutting-edge technological advances, and engaging discussions that promise to strengthen the field of ophthalmology. The TROPHY Ophthalmic Conference is Trent Ophthalmic Society's flagship event, provides...In conversation with Professor Usha Chakravarthy (2018)
1 March 2019
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EYE - Vitreo-Retinal, EYE - General
Professor Chakravarthy popped by the Eye News stand at the 2018 Royal College of Ophthalmologists Annual Congress after her excellent Bowman Lecture. She gave us a summary of her presentation, which looked at how our understanding of AMD has changed...
Results of fixed aflibercept treatment regime in type 3 neovascularisation
1 April 2020
| Sofia Rokerya
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EYE - Vitreo-Retinal
In this prospective study the authors evaluate the effect of intravitreal aflibercept injections in the treatment of naive type 3 neovascularisation using a fixed treatment regime. Fourteen eyes of 14 patients were studied. All patients were treated with intravitreal 2.0...
Pegcetacoplan: A breakthrough treatment for dry age-related macular degeneration?
Age-related macular degeneration (AMD) is a degenerative condition affecting the macula, the part of the retina responsible for central vision. It is characterised by the presence of drusen and retinal pigment epithelium (RPE) abnormalities in the absence of other macular...Progression of myopic maculopathy after treatment
1 October 2014
| Sofia Rokerya
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EYE - Vitreo-Retinal
The authors report on a retrospective study carried out to evaluate long-term progression of myopic maculopathy and functional outcome in eyes treated for myopic choroidal neovascularisation (CNV) and in eyes without CNV. Fifty-four myopic eyes of 30 patients were included...
Risk of CNV related to angioid streaks in PXE
7 April 2021
| Tasmin Berman
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EYE - Vitreo-Retinal
This retrospective cross-sectional study investigated 301 patients with pseudoxanthoma elasticum (PXE) for prevalence of choroidal neovascularisation (CNV) and macular atrophy. Some patients were excluded due to missing or poor-quality imaging or the fact that they didn’t have angioid streaks, leaving...
Lacquer cracks
1 August 2019
| Saruban Pasu
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EYE - Vitreo-Retinal
The purpose of this Japanese study was to analyse the morphologic features and natural progression patterns of lacquer cracks (LC). The presence of linear hyperfluorescence on the fundus fluorescein angiography (FFA) was used as the standard for diagnosing the presence...