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Diagnosis and management of solitary fibrous tumour

This is a retrospective review of 21 patients diagnosed with solitary fibrous tumour of the orbit between 1996 and 2018 at a single centre. The authors reviewed the clinical presentation, management and course of the disease and reanalysed the histopathology...

Differential diagnosis of retinoblastoma and pseudo retinoblastoma

The authors reviewed the rate of pseudo retinoblastoma (PRB) among cases referred for suspicion of RB at a tertiary referral centre in Turkey and the distribution of PRB cases according to age. This was a retrospective study of 549 patients...

Diagnosis of amiodarone-associated optic neuropathy

Amiodarone is a widely used anti-arrhythmic drug. Several case reports describe optic neuropathy which has been linked to its use. This case series discusses the diagnosis of amiodarone-associated optic neuropathy (AAON) and its potential impact on cardiac therapy. The authors...

Differential diagnosis of inflammatory optic neuritis

The authors present the differential diagnosis of inflammatory optic neuritis (ON) to include multiple sclerosis, infectious optic neuritis, systemic disease and neuromyelitis optica (NMO). The features of ON for the varying aetiologies are detailed including incidence and overlap. In acute...

Diagnosis and management of orbital vascular malformations

This is an authoritative review of a controversial and difficult clinical area. The authors have experience of over 350 cases and provide a well-structured review of the classification and management of orbital vascular malformations. They emphasise the need to understand...

Spot diagnosis? The white dot syndromes

This review article provides an up-to-date summary of white spot syndromes. The authors explain that the white spot syndromes form a group of inflammatory retinal disorders with distinct lesion distribution and progression patterns. Multimodal imaging has revealed unique phenotypes, enhancing...

Alternative diagnosis in cases of poor response to amblyopia therapy

The aim of this study was to assess the prevalence of coexistent ocular pathology and identify / describe the factors that contribute to undiagnosed alternate diagnosis and / or co-existent pathology at initial presentation in patients referred as potentially amblyopic....

Glaucoma diagnosis after paediatric cataract surgery

The authors undertook a retrospective review of patients with glaucoma after congenital cataract surgery and report clinical presentation, treatment and long-term outcomes at a tertiary referral centre. The study included 58 eyes of 42 patients of which 59% were male....

My Top Five: Innovations in the diagnosis of ocular tumours

Ocular tumours can vary widely in origin, from benign growths to metastases from distant disseminated malignancies. Although rare, ocular tumours pose a significant health and economic burden globally, with ocular cancers accounting for 0.2% of all diagnosed malignancies in the...

Assaying acetylcholine receptor antibodies in the diagnosis of ocular myasthenia

Myasthenia gravis (MG) is an autoimmune disease that leads to impaired neuromuscular transmission. Solely ocular manifestations of MG (OMG) occur in 15-50% of cases, most frequently in the form of fluctuating ptosis and diplopia. Most cases of OMG convert later...