You searched for "epinuclear"
Delayed EPBRT efficacy in retinoblastoma
1 October 2019
| Jonathan Chan
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Paediatric Ophthalmology / Strabismus
This is a retrospective medical records review of 50 patients (54 eyes) with retinoblastoma (RB), who received I-125 episcleral plaque brachytherapy (EPBRT) prior to (primary) or following chemoreduction (delayed) alone and in combination with non-irradiative focal therapy. Fifty-six plaques were...
Supranuclear ocular motility disorders
Figure 1: Bilateral INO Introduction Complex ocular motility disorders are a diagnostic challenge. These patients come with very complex ocular motility presentations and require a careful and detailed assessment in order to find the correct diagnosis and arrange appropriate investigations....Insects, swelling and sight loss: a case of orbital inflammatory syndrome
1 June 2022
| Parushak Rezai, Susan Sarangapani
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EYE - General
Despite being the most common cause of painful orbital mass in adults and the third most common orbital disease, orbital inflammatory syndrome still proves to be a difficult ocular condition to diagnose, treat, and manage. A 41-year-old lady presented to...
Aug/Sep 2014 Quiz 1
1 August 2014
| Hardeep Singh Mudhar, Sachin Salvi
|
EYE - Cataract, EYE - Cornea, EYE - Glaucoma, EYE - Imaging, EYE - Neuro-ophthalmology, EYE - Oculoplastic, EYE - Oncology, EYE - Orbit, EYE - Paediatrics, EYE - Pathology, EYE - Refractive, EYE - Strabismus, EYE - Vitreo-Retinal, EYE - General
History A 50-year-old female with a history of smoking, weight loss and cough presents to the ophthalmology clinic with a distorted pupil. Examination reveals a mass on the surface and within the iris (see Figure 1). The ophthalmologists decide to...
The Sclera and Systemic Disorders (3rd Edition)
An interesting historical introduction captures the reader’s attention as the journey begins into exploring the peculiarities and pathologies of ‘dura tunica of Vesalius’, a term coined by anatomists of the middle ages. This refers to what we today identify as...
Episcleral brachytherapy (EB) for retinoblastoma (RB)
5 June 2020
| Jonathan Chan
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EYE - Pathology, EYE - Oncology
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episcleral brachytherapy, focal consolidation therapy, ocular survival, recurrence-free survival, retinoblastoma
This retrospective study consisted of 11 eyes treated either with Iodine (I) -125 or Ruthenium (R) -106EB with a mean apical dose of 44Gy. There were five in group B (46%), three in group C (27%) and three in group...
Sustained elevation of extracellular ATP in chronic glaucoma
1 August 2015
| Wai Siene Ng
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EYE - Glaucoma
Although adenosine 5′-triphosphate (ATP) release from retinal neurons and astrocytes has been demonstrated in short-term increases in intraocular pressure (IOP); such as in aqueous humor of humans with primary acute angle closure glaucoma, the response in chronic IOP elevation was...
Brn3b neuroprotective effect in rat glaucoma model
1 April 2015
| Wai Siene Ng
|
EYE - Glaucoma
An adeno-associated virus-directed overexpression of the Brn3b protein in hypothesised to confer neuroprotective effects in this paper. This is ultimately tested in a well-accepted rat glaucoma model (Morrison’s model: saline injection into episcleral veins of rat eyes with a force...
Brimonidine day and night time IOP
1 October 2014
| Lorraine North
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EYE - Glaucoma
The authors describe a randomised double masked study of 29 participants with ocular hypertension (OHT) who either self-administered 0.2% brimonidine or placebo three times daily for six weeks. Patients were seen during day time and night time visits and had...
Intermittent manual compression for CCF
Carotid cavernous fistulae (CCF) can be classified as high and low-flow or as having direct and indirect communication. Most commonly, management of high-flow CCF is with endovascular embolisation. The authors look at an alternative treatment for CCF in indirect low-flow...Unravelling ocular motility
1 April 2016
| Damien CM Yeo
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EYE - Neuro-ophthalmology
Ocular motility can often be a slightly abstract concept during the earlier years of ophthalmology training. A large variance on what embodies normality; mythical concepts like fusion and binocular vision, examination techniques that can be fiddly, and complex neuroanatomy all...
Lessons from an unusual case of syphilis
3 August 2023
| Ryian Mohamed, Shaman Dolly, Jonathan Than, Shweta Anand
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EYE - Vitreo-Retinal
The rise of syphilis transmission rates over the past two decades has been one of public health’s great puzzles. In the UK, the situation has reached epidemic levels, with a 126% increase between 2013 and 2018 [1]. We present a...
