You searched for "eye disease"
Tear production levels and dry eye disease
1 April 2019
| Kurt Spiteri Cornish
|
Cornea / External Eye Disease
|
Dry eye disease, Schirmer I test, clinical tests, large population of patients, tear production levels
Dry eye disease (DED) is multifactorial, caused by an alteration in the quality or quantity of tear film’s three layers. Several tests are available for diagnosis. The aim of this study was to determine if the Schirmer test (ST) could...
Visual field changes in thyroid eye disease (TED)
1 April 2018
| Jaya Myneni
|
Oculoplastics, Orbit
|
Thyroid eye disease, compressive optic neuropathy, visual field
This study is a retrospective non- comparative review of visual field (VF) tests in patients with compressive optic neuropathy from thyroid eye disease (TED-CON). Ninety-six visual fields in 68 patients were included in the study and a two-step analysis of...
VDT use and dry eye disease in children
1 February 2015
| Fiona Rowe (Prof)
|
Paediatric Ophthalmology / Strabismus
There has been an increase in the amount of work performed using video display terminals. This study compared school children with and without dry eye disease and evaluated the risk factors of dry eye disease and evaluated the risk factors...
No risk of dry eye disease in concomitant strabismus cases
2 August 2024
| Fiona Rowe (Prof)
|
Paediatric Ophthalmology / Strabismus
This preliminary assessment of the ocular surface of patients with concomitant strabismus before surgery was undertaken to determine if the presence of strabismus increases the risk of dry eye disease. This was a cross-sectional study of 204 patients with concomitant...
Colour Doppler imaging before and after orbital decompression in thyroid eye disease
2 December 2019
| Rina Bhatt
|
Oculoplastics, Orbit
|
Color Doppler imaging, orbital decompression, thyroid eye disease
In this prospective, uncontrolled study euthyroid patients with moderate to severe inactive thyroid eye disease underwent colour Doppler imaging before and after orbital decompression. Patients with dysthyroid optic neuropathy, corneal breakdown, systemic disease (diabetes, cerebrovascular accident, cardiovascular and peripheral vascular...
Benefit of selenium and vitamin D supplementation in thyroid eye disease
1 April 2020
| Claire Howard
|
Neuro-Ophthalmology
There is some limited evidence of as association between thyroid eye disease (TED) and nutritional deficiencies including selenium and vitamin D. Prior studies show that selenium can reduce TPO-antibody concentrations and improve hypothyroidism and post-partum thyroiditis. Limited evidence also shows...
Can 3D facial imaging improve patient management in disfiguring eye disease?
Fight for Sight is the leading UK charity funder of eye research. Since the 2013 Sight Loss and Vision Priority Setting Partnership we have encouraged our researchers to work on priorities jointly identified by people affected by sight loss and...Sickle cell eye disease: an overview of vitreoretinal complications and their surgical management
1 December 2016
| Antonio Berarducci, Tom Williamson
|
Retina / Uvea / Vitreous
Sickle cell disease is the most common genetic disorder worldwide and is associated with lifelong anaemia, intermittent pain and multi-organ morbidity. Ocular involvement can be associated with significant visual impairment due to the complications of proliferative sickle retinopathy (PSR). Occasionally...
Eye disease patients have more opportunity than ever to take part in NHS research studies
1 November 2018
|
AMD, Cataract and Refractive, Cornea / External Eye Disease, Emergency Ophthalmology, Genetics, Glaucoma, Imaging, Neuro-Ophthalmology, Ocular Pathology and Oncology, Oculoplastics, Ophthalmology, Optometry, Orbit, Paediatric Ophthalmology / Strabismus, Retina / Uvea / Vitreous, ONLINE EXCLUSIVE ARTICLES
A new report highlights how 76% of UK hospitals now offer patients the opportunity to take part in studies of eye disease to improve research and innovation. ‘Ophthalmology research in the UK’s National Health Service: the structure and performance of...
Tear film thickness after treatment with artificial tears in patients with moderate dry eye disease
1 June 2015
| Sharmina Khan
|
Cornea / External Eye Disease
In recent years artificial tear drops addressing tear film osmolarity have come onto the market. Increased tear evaporation and reduced tear volume results in tear hyperosmolarity. This triggers an inflammatory process leading to apoptosis of goblet and epithelial cells. Trehalose,...
Exploring the potential of neurodegenerative disease screening within age-related eye disease research
3 August 2023
| Lauren R Hepworth
|
Neuro-Ophthalmology
The authors recruited healthy controls aged between 60 and 75-years-old, previously enrolled into a registry as patients following cataract surgery without age-related macular degeneration (AMD). Exclusion criteria included dense cataract, retinal disease, ocular inflammatory disease, moderate glaucoma, optic neuropathy, cancer,...
Low dose steroids for ocular dry eye disease in graft vs. host disease
1 August 2018
| Tasmin Berman
|
Cataract and Refractive
This double-masked randomised clinical trial compared the response of dry eye disease (DED) to treatment with topical steroids in patients with and without graft vs. host disease (GVHD). Forty-two patients in a single centre (n=21 with and n=21 without GVHD)...