You searched for "inflammatory"
OCT in peripheral corneal thinning
This small retrospective study used high resolution optical coherence tomography (OCT) Heidelberg Spectralis to identify features which could determine the underlying aetiology of peripheral corneal thinning. Ten patients were included; five with diagnoses of degenerative peripheral thinning; Terrien’s marginal degeneration...
RPE use similar pathway to regulatory T cells to inhibit immune response
Retinal pigment epithelial (RPE) cells form an important part of the blood-retinal barrier that protects the neuronal cells responsible for sight. RPE cells are involved in innate and adaptive immune responses via expression of surface molecules and release of cytokines....
Effects of market competition on the price of topical eye drops in the US
The authors retrospectively examined the relationship between the number of Federal Drug Administration (FDA)-approved manufacturers and the price change of generic and branded topical eye medications based on the formulations listed in the FDA Orange Book and the National Average...Moorfields Education International Uveitis Symposium
Don't miss this chance to hear from top national and international speakers, including symposium organiser Professor Carlos Pavesio, Consultant Ophthalmologist and uveitis specialist at Moorfields Eye Hospital and Director of the Scientific Organizing Committee. This unique three day symposium will provide a forum for the exchange of information and new ideas relevant to clinical practice, investigations, and therapeutic management of patients with ocular inflammatory diseases and complex uveitic conditions, with an in-depth discussion surrounding the diagnosis and therapeutic strategies of specific inflammatory disorders.
Trochleitis features
The authors evaluate the epidemiology, clinical signs, treatment and outcomes of trochleitis in a retrospective review of 59 cases. Estimated prevalence was 12 per 100,000. Eighty-six percent were female and mean age was 43±18 years. All but one case was...
Somatostatin protects retinal pericytes
Diabetic retinopathy (DR) is a complication of diabetes, caused by high blood sugar levels damaging the retinal microvasculature. Mechanisms, such as oxidative stress and deposition of advanced glycation end products, leads to glial cell activation and neuronal apoptosis. Pericytes, contractile...
Choroidal thickness in ocular sarcoidosis by OCT measurement
This is the first study to evaluate the choroidal thickness in patients with ocular sarcoidosis during the quiescent phase using enhanced depth imaging optical coherence tomography (EDI-OCT) and comparing with normal subjects. Ocular sarcoidosis may affect the choroidal circulation (occlusive...
ANGPTL-4 inhibition reduces inflammation in diabetic retinopathy
Diabetic retinopathy (DR) is the most common cause of blindness in working-age humans, and numbers are rising due to increased cases of type 2 diabetes (T2D). T2D is associated with increased obesity and dyslipidaemia, which is a major risk factor...
Mast cells in Graves’ ophthalmopathy
Graves’ ophthalmopathy (GO) is a potentially sight-threatening ocular disease, occurring in patients with hyperthyroidism due to Graves’ disease. Also known as thyroid-associated ophthalmopathy, GO is characterised by orbital infiltration by immune cells including macrophages, T cells and plasma cells, which...
Ovarian hormones drive onset of Sjogren’s disease in mice
Sjogren’s syndrome (SS) is a debilitating, sight-threatening, systemic autoimmune disease with no effective treatment available. SS is characterised by lacrimal gland lymphocytic infiltration and epithelial cell death, as well as by the presence of serum autoantibodies. Patients have severe dry...
Safety and outcome of microincision vitreous surgery in uveitis
This paper reports the outcomes of microincision vitreous surgery (MIVS) 23G/25G in uveitis of 103 patients (106 eyes) who underwent diagnostic MIVS over a period of four years at the Advanced Eye centre in Chandigarth India. The postoperative evaluation included...
