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Correlation between structural and functional status of optic nerve and retina in multiple sclerosis

Multiple sclerosis (MS) involves autoimmune inflammatory demyelination and axonal degeneration in the central nervous system. Investigation of the retina and optic nerve head (ONH) is an ideal way to visualise this demyelination. This study investigates the functional and structural properties...

Time domain vs. spectral domain in the measurement of the optic nerve head

The authors describe a prospective study of 40 participants (20 healthy and 20 with glaucoma) enrolled to compare the measurements of the optic nerve head (ONH) parameters given by time domain (TD) and spectral domain (SD) optical coherence tomography (OCT)....

Optic nerve head perfusion response to reduced blood pressure and increased intraocular pressure

The purpose of this prospective study was to test the hypothesis that blood flow autoregulation in the optic nerve head has less reserve to maintain normal blood flow where there is a blood pressure induced decrease in ocular perfusion pressure...