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IAC vs. IVC chemotherapy for RB
This a single centre retrospective review of consecutive patients between 1997 and 2014, of all sporadic unilateral retinoblastoma (RB) group D cases, treated with combined intravenous chemotherapy (IVC) and focal treatments (1997- 2008), or intra-arterial chemotherapy (IAC) treatment (2008 to...
Finasteride and central serous chorioretinopathy
The pathophysiology of central serous chorioretinopathy (CSC) is complex and has not been fully elucidated. Suggested theories include hyperpermeability and increased hydrostatic pressure in the choroidal vasculature, which creates RPE detachments overwhelming the RPE barrier function, leading to accumulation of...
Atopic keratoconjunctivitis (AKC) and ocular surface squamous neoplasia (OSSN)
The authors present two cases of invasive OSSN in patients with severe AKC. Case 1 was a 73-year-old male with severe AKC and atopic eczema who developed a suspicious papillary-like limbal lesion in the left eye. He had an excisional...
Risk factors for intraoperative floppy iris syndrome
Intraoperative floppy iris syndrome (IFIS) is charcterised by flaccid iris stroma leading to fluttering and billowing of iris, tendency of iris to prolapse through surgical incisions and causing intraoperative pupil constriction. IFIS is characterised as complete when all three features...
Late stromal rejection in DALK
This case series reported on late stromal rejections in eyes after uncomplicated deep anterior lamellar keratoplasties (DALKs). Four eyes of three patients experienced episodes of isolated stromal rejection 33 to 46 months after surgically uncomplicated DALKs and a minimum of...
Suspected vitreous seeding of uveal melanoma
This is a retrospective non-randomised study of 23 patients with consecutive uveal melanoma who underwent diagnostic vitrectomy between the period of January 2000 and November 2013. The reason for vitrectomy was suspected dissemination of tumour cells inside the eye. The...
Serology testing in periocular inflammatory disease
This is a review article of serological tests in thyroid eye disease, IgG4-related disease and myasthenia gravis. The authors provide an overview of the current serology with a brief description of how they relate to the pathogenesis of each condition....
Intravitreal bevacizumab vs. triamcinolone in patients with DMO at the time of cataract surgery
This prospective, single masked randomised control trial (RCT) compared visual and anatomical outcomes when either intravitreal bevacizumab (BVB) or triamcinolone (TA) was administered at the time of cataract surgery and at subsequent review, if required, in patients with diabetic macula...
Froben for anterior scleritis
Flurbiprofen (Froben) is one of the nonselective cyclooxygenase (COX) inhibitors blocking both COX-1 and COX-2 pathways. Agrawal et al. undertook a retrospective cohort study to determine the effectiveness of oral Froben in managing noninfectious, non-necrotising anterior scleritis. One hundred and...
Management of congenital NLD obstruction
The authors evaluated changes in management of congenital nasolacrimal duct obstruction (CNLDO) by surveying 1495 Association for Paediatric Ophthalmology & Strabismus (AAPOS) members. The survey consisted of 21 multiple choice questions with anonymised return. Responses were received from 127 members...
Are retinal vein occlusions seasonal? And if so why might that be?
Some studies have reported a strong seasonal pattern to central retinal vein occlusion (CRVO) occurrence with a peak in January, but other studies have failed to replicate this finding. The authors sought to determine data for Stockholm’s seasonal variation in...
