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Does Acanthamoeba need bacteria to cause keratitis?
An animal study was carried out on 36 rabbits, whose corneas were inoculated with either Acanthamoeba castellanii alone, Pseudomonas aeruginosa alone or both pathogens together after a period of short (two hours) or long (six hours) co-incubation. The clinical severity...
Risk factors for DSEAK graft detachment
This was a retrospective data review on all patients who underwent primary descemet stripping automated endothelial keratoplasty (DSEAK) during a 10 year period: 1212 eyes were included in the analysis. Postoperative graft detachment occurred in 45 eyes (3.7%) and required...
Corneal lenticule allotransplant
This animal study looked at corneal lenticule allograft transplantation in rabbits. Seven rabbits underwent small incision lenticule extraction (SMILE) procedures, where their stromal lenticules were extracted and transplanted fresh into pre-prepared corneal stromal pockets of seven recipient eyes. Animals were...
Treatment options for septic cavernous sinus thrombosis
Septic cavernous sinus thrombosis is a rare but serious complication of infection of the cavernous sinuses. Potential therapies include antibiotics, corticosteroids and anticoagulation, as well as surgical intervention for source control of the infection. The authors report that there is...
Resolution of idiopathic intracranial hypertension (IIH): case series
The authors report the findings from 14 patients following treatment for idiopathic intracranial hypertension (IIH). All 14 patients experienced an immediate and sustained resolution of the IIH in the setting of prolonged cerebrospinal fluid (CSF) drainage at a rate greater...
Histopathological changes in rabbit retinitis pigmentosa
The authors report the histopathological changes of retinal ganglion cells (RGCs), optic disc and optic nerve in rabbit with advanced retinitis pigmentosa (RP). RP was recreated in rabbits by using bacterial artificial chromosome transgenesis, with the purpose of increasing understanding...
ROP incidence and treatment profile over time
The primary aims of this study were to report the incidence of severe ROP and its treatment in infants <27 and 30 weeks gestational age. Secondary aims were to compare this data with three previously reported cohorts: 2003-2005; 200/2550 with...
Extraocular muscle OCT
The goal was to evaluate the use of the Heidelberg anterior segment optical coherence tomography (AS-OCT) to image extraocular rectus muscle insertions and to expand the use of the AS-OCT to also image vertical rectus muscles. The authors evaluated inter...
