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Online retinoblastoma surveillance tool

Given the vision and life-threatening course of retinoblastoma (RB), it has become a significant heritable childhood cancer to screen for. To recommend surveillance, risk must be estimated and genetic testing plays a vital role. However, genetic tests vary based on...

Nepafenac punctal plugs after cataract surgery: a new alternative?

The nepafenac punctal plug delivery system (N-PPDS) is an experimental L-shaped plug made of nonbiodegradable, preservative-free medical-grade silicone. It can deliver a sustained level of nepafenac for six weeks. This is a prospective, randomised, parallel-arm, double-masked, placebo-controlled, phase II pilot...

Real world results of cataract surgery in pseudoexfoliation

In this single-centre retrospective cohort study, the data of pseudoexfoliation (PXF) patients undergoing phacoemulsification cataract surgery from January 2010 to December 2019 was analysed in the National Health Service setting. The study comprised 23,329 eyes of 15,257 patients. Patients with...

Profile of sports-related ocular trauma

The authors conducted a previous study on the epidemiology of sports-related ocular trauma in Quebec. In this study they aim to gather further information on presentation via ophthalmology and emergency departments. They undertook a follow-up study from a tertiary care...

ROP anti-VEGF treatment review

The purpose of this review was to consider data relating to risks and benefits of the use of anti-VEGF treatment for retinopathy of prematurity (ROP) over the past five years of 2015-2020. Ocular benefits include treatment of aggressive posterior ROP,...

Ocular toxoplasmosis

This is a retrospective study of 106 patients between March 2011 and June 2018, of 37 IgM + group and 69 IgM - group of patients. The clinical features, demographics of patients with ocular toxoplasmosis (OT) were studied according to...

Why is there subretinal fluid at the macula?

This is a review article looking at the differential diagnosis of subretinal fluid in the macula that could be diagnosed as central serous chorioretinopathy (CSCR). The authors have categorised them into 12 groups: neovascular diseases, vitelliform lesions, inflammatory diseases, ocular...

Proning and ocular injury

This systemic review and meta-analysis investigated the incidence and type of ocular injuries reported in adult critical care from both prone and supine patients between January 1990 and July 2020. They reviewed 11 randomised controlled trials. In three trials, 28...

Uveitis ocular toxoplasmosis

This is a retrospective study of 106 patients between March 2011 and June 2018, of 37 IgM +group and 69 IgM - group of patients. The clinical features, demographics of patients with ocular toxoplasmosis (OT) were studied according to the...

Amniotic membrane transplantation for SJS/TEN

This is a retrospective study of consecutive patients who underwent amniotic membrane transplantation (AMT) in the acute stage of Stevens-Johnson syndrome (SJS) / toxic epidermal necrolysis (TEN) from Toronto, Canada, between 2009 and 2018 and had more than three months...

Hidden spread of sebaceous cell carcinoma

This was a review of 29 patients who had undergone orbital exenteration for sebaceous cell carcinoma. Prompted by the increasing use of topical treatments for intraepithelial disease, the authors were keen to discover the frequency of spread of tumour cells...

Care journeys of patients with central retinal artery occlusion

The authors present a retrospective case note review of all adult patients referred for or diagnosed with central retinal artery occlusion (CRAO) to a single tertiary hospital over a 10½ year period. A total of 181 patients were included in...