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Effects of ML4 on the eye
Mucolipidosis type IV (ML4) is an autosomal recessive lysosomal storage disease and is caused by variants of the MC0LN1 gene. It often presents in young individuals with eye and ocular adnexa issues. The authors present a case report and literature...
Bioengineered human tissue
This is a literature review of the current status of tissue engineering related to ocular and oculoplastic reconstructive surgery. The authors describe the process of bioengineering for tissue reconstruction. The aim is to reproduce functional tissue by the use of...
Retinal structural features of CMV retinitis
Confocal adaptive optics (AO) technology has enabled cellular level retinal imaging, including imaging of photoreceptors and blood flow. Adaptive optics scanning laser ophthalmoscopy (AOSLO) is a technology that provides high resolution and high contrast retinal images by correcting ocular aberrations....
Outcomes of corneal collagen crosslinking (CXL) in pseudophakic bullous keratopathy (PBK)
This was a retrospective non-comparative, interventional case series of 50 eyes in 50 patients with symptomatic PBK who underwent CXL (epithelium-off). Central corneal thickness (CCT), pain score, best corrected visual acuity (BCVA), and corneal transparency were recorded at baseline; at...
Topography based keratoconus progression after corneal collagen cross-linking
Case 1 describes a 35-year-old man with progressive keratoconus (PK). His best corrected visual acuity (BCVA) was right 20/80 (-5.25/-7.75 x 85) and left 20/20 (+4.75/-5.00 x 90). His Ks were right 36.32/48.02 D and 41.15/46.41 D. Right central cornea...
Inflammatory macular holes
The authors present a case of closure of a full thickness macular hole in a patient with Behçet’s disease, without surgery. The 23-year-old male they describe presented with a history of recurrent oral aphthous ulcers and a genital ulcer. Ocular...
Long-term results of cross-linking treatment for keratoconus
The authors report on the long-term outcomes in a prospective case series of patients with keratoconus undergoing corneal collagen cross-linking (CXL) treatment. Thirty-two patients (40 eyes; mean age 22.5+/-5.5 years) with Grade I, II and III progressive keratoconus were recruited...
Contrast sensitivity in myopic eyes
A classification system has been proposed for myopic maculopathy: grade 0 (no myopic retinal lesions), grade 1 (tessellated fundus), grade 2 (diffuse chorioretinal atrophy (CRA)), grade 3 (patchy CRA), and grade 4 (macular atrophy). Tessellated fundus is defined as the...Sharing best practice and landmark evidence in glaucoma care
Evolving technology, best practice and landmark evidence in glaucoma care were reviewed by an international expert faculty in session presentations and debates during the 11th Moorfields International Glaucoma Symposium 2019. The authors were meeting chairs and provide an overview of...Choroidal folds
Choroidal folds are undulations of the choroid, Bruch’s membrane and pigment epithelium, with wrinkling of the overlying retina. They may be idiopathic but can also be caused by a number of different conditions. Case report A 60-year-old male patient was...
Characteristics of limbal lymphatic vasculature on confocal microscopy
This ex vivo study aims to describe the morphological characteristics of the human limbal lymphatic vasculature using confocal microscopy and immunofluorescence. Twelve corneal specimens are obtained from human donor eyes. These corneal buttons are not suitable for transplantation due to...
