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Treatment options for septic cavernous sinus thrombosis

Septic cavernous sinus thrombosis is a rare but serious complication of infection of the cavernous sinuses. Potential therapies include antibiotics, corticosteroids and anticoagulation, as well as surgical intervention for source control of the infection. The authors report that there is...

What to expect when meeting a statistician

There are a growing number of statisticians working closely with ophthalmologists. They have different training but they are driven by the same goal: to perform high quality evidence based clinical research [1,2]. In a perfect world we would simply conduct...

How to consent patients

I attended a morning seminar at the recent College Congress in Liverpool about how to properly and legally consent a patient for a procedure. There has been a lot of interest in this of late following the Montgomery ruling, in...

Demystifying external trainee selected components and out of programme experiences

If you don’t know your external TSCs from your OOPC/OOPT/OOPE/OOPR, then this article is for you. Trainee selected components (TSC) are College-approved periods of training, usually ranging from six months to a year (formally ASTO) of intensive subspecialty training in...

The role of injection assistant devices in establishing a nurse-led AMD service

The author shares his experience of setting up a nurse-led service to deliver anti-VEGF intravitreal injections and how injection assistant devices supported training. Age-related macular degeneration (AMD) has become a leading cause of irreversible blindness [1]. It is estimated that...

The fragile p-value

Abdus Samad Ansari explores the limitation of the p-value and the application of the fragility index in clinical trials. Clinical trials and tribulations? The restoration of vision or more purely the gift of sight is an aspect of care that...

Can thou lyse this? A national study of emergency canthotomy and cantholysis

Eighty-two-year old Janet Smith woke up on the floor. Had she been unconscious? Her head hurt. It was the middle of the night, but in the darkness she suddenly wasn’t sure whether she could see out of her right eye....

Glaucoma UK launches the Pitts Crick Career Development Fellowship in celebration of its golden jubilee anniversary

Glaucoma UK is a leading charity dedicated to supporting those affected by glaucoma. The charity is proud to announce the establishment of the Pitts Crick Career Development Fellowship, a three-year post-doctoral research fellowship awarded to help mark the charity’s golden jubilee anniversary. The fellowship will support a rising star within glaucoma research, who the charity hopes will go on to play a pivotal role in transforming glaucoma diagnosis or treatment into the future.

Restoration of colour perception in patients with retinitis pigmentosa

This is a case series testing the feasibility of using bioelectronic retinal prostheses to partially restore colour perception in seven patients with advanced retinitis pigmentosa. Bioelectronic retinal prostheses are able to bypass degenerated photoreceptors to directly stimulate the inner retinal...

Rare eye diseases: progress continues with authorised orphan medicines and breakthrough technologies

An update on the development of orphan medicines, recent regulatory treatment approvals for rare eye conditions and advances in retinal prosthetic technologies for blinding diseases. The prevalence of a rare disease is based usually on a range of estimates and...

Aug/Sep 2015 Quiz 1

History A 60-year-old woman was referred to ophthalmology with a suspected left eye choroidal naevus. Visual acuity was unaffected in both eyes and she was asymptomatic. Ocular history and medical history were unremarkable. Questions Figure 1: Fundus photograph. 1. What...

Possible COVID-19 related maculopathy

COVID-19 is being investigated as a potential cause for various ocular diseases, with growing evidence of related retinal vascular changes, that vary from isolated cotton wool spots and retinal haemorrhages to retinal vascular occlusions [1.2]. COVID-related macular affection has also...