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HtrA1 enhances cell senescence

A genetic basis for age-related macular degeneration (AMD) has been greatly advanced in recent years. The role of identified pathways such as complement factor H in AMD has been widely investigated. However, the effect of other gene variants identified by...

Efficacy and safety of novel PF brimonidine / timolol fixed-combination ophthalmic solution for OAG

This study is a multicentre, randomised, open-label, parallel-group clinical trial to evaluate the efficacy and safety of a newly developed preservative-free (PF) brimonidine / timolol fixed-combination (BTFC) ophthalmic solutions as compared with preservative-containing (PC) BTFC ophthalmic solution in adult patients...

Risk factors for further surgery in consecutive ET

The preoperative and postoperative factors around first surgery for exotropia were investigated for predicting second surgery for consecutive esotropia. Fifty-two patients with consecutive esotropia after exotropia surgery were reviewed: 17 required surgery for the esotropia and 35 did not. There...

Strabismus in bilateral pseudo-aphakes

The authors evaluated ocular deviation and near stereopsis for five years after bilateral cataract surgery in 88 patients. The results showed that patients with preoperative near exophoria angle greater than 12PD progressed more rapidly to intermittent exotropia after surgery with...

Diplopia after orbital decompression

This is a review of patients undergoing a balanced two-wall and fat orbital decompression to identify risk factors for new onset diplopia. Standard decompression techniques were used, but as the surgery was conducted by ENT surgeons, the medial walls were...

Simultaneous vs. alternate PCT disparity in XT

The authors quantified the relationship between simultaneous prism and cover test (SPCT) and alternate prism and cover test (APCT) alignment in patients with measures at the same visit after surgery for exotropia. This was a retrospective study of 955 patients...

Hering’s response in ptosis surgery

his is a prospective study of the Hering’s response in patients undergoing Muller’s muscle-conjunctival resection (MMCR) ptosis surgery, with a particular reference to the accuracy of preoperative phenylephrine testing. Patients with unilateral ptosis were assessed clinically preoperatively, in the immediate...

LASEK with mitomycin C to correct myopia in thin corneas

This study evaluated the long-term outcomes of laser-assisted subepithelial keratomileusis (LASEK) with intraoperative use of mitomycin C (MMC) performed on thin corneas for the correction of myopia. MMC modulates the corneal wound healing response in surface healing, thus reducing the...

Consecutive exotropia features

This study sought to detect abnormal scleral attachment with comparison of histopathological findings in consecutive exotropia. The study also considered the success rate of medial rectus resection and advancement, dose response and evaluate potential preoperative factors that might indicate presence...