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Licence to save: a UK survey of anti-VEGF use for the eye

1 February 2017 | | EYE - Vitreo-Retinal
This comment article highlights the controversy that exists in the choice for anti-VEGF drugs used for treatment of macular oedema and wet age-related macular degeneration (AMD). Two existing licensed drugs for macular oedema are ranibizumab (Lucentis) and aflibercept (Eylea). A...

Stereotactic radiotherapy for polypoidal choroidal vasculopathy

1 August 2015 | | EYE - Vitreo-Retinal
Polypoidal choroidal vasculopathy (PCV) is a variant of neovascular AMD. It is a disease of choroidal vasculature characterised by abnormal branching vascular network with aneurysmal dilatations (polyps). Features of PCV include pigment epithelial detachments (PED), subretinal fluid (SRF) accumulation and...
Ophthalmologica journal cover image.

Displacement of submacular haemorrhage – comparative study pneumatic displacement versus subretinal cocktail injection

3 October 2024 | | EYE - Vitreo-Retinal
The authors report a multicentre retrospective interventional case series study comparing the outcome of submacular haemorrhage (SMH) using pneumatic displacement with intravitreal expansile gas versus treatment with pars plana vitrectomy (PPV) versus subretinal injection of tissue plasminogen activator (tPA), anti-vascular...

AI can identify treatment gaps for patients with macular disease, study shows

10 November 2025 | artificial intelligence, AMD, new studies, treatment analysis
Using artificial intelligence (AI) in eye clinics could reduce both undertreatment and overtreatment of neovascular or ‘wet’ age-related macular degeneration (AMD). AMD is the leading cause of irreversible vision loss in older people and accounts for around 1 in 10...

The approach to angle-closure glaucoma

1 October 2016 | | EYE - Glaucoma
Further to my last article in Eye News (print issue) describing the diagnostic approaches to various clinical scenarios in glaucoma, the approach to angle-closure glaucoma (ACG), a situation terrifying for patient and registrar alike, will be discussed. Please refer to...

Do patient demographics influence AMD clinic attendance during COVID-19 lockdown?

3 June 2021 | | EYE - Vitreo-Retinal
The authors assess the impact of the COVID-19 pandemic on adherence to scheduled clinic appointments among age-related macular degeneration patients in a clinic in North Wales. The COVID-19 pandemic has significantly affected the population, affecting economic and social wellbeing, whilst...

Full thickness macular hole after YAG PI

1 April 2015 | | EYE - Glaucoma
The authors report a case of macular hole post YAG peripheral iridotomy (PI) of a patient with pre-existing vitreomacular adhesion. Although a relatively safe procedure, some anterior segment complications are well documented such as corneal endothelium damage, rise in IOP,...

Update on emerging therapies for age-related macular degeneration

4 December 2023 | | EYE - Vitreo-Retinal
The 23rd European Society of Retina Specialists (EURETINA) Congress, held in Amsterdam, the Netherlands, provided a timely update on anti-complement therapy for geographic atrophy and emerging investigational therapies for neovascular age-related macular degeneration. Anti-complement therapy for geographic atrophy Geographic atrophy...

Transforming eyecare with AI at 100% Optical

4 March 2024 | Pearse Keane, AI, Moorfields, UCL, technology, advancement, artificial intelligence, development
“We are drowning in people we need to see in hospital eye services, and some people are going blind as a result. We are looking at nearly 10m hospital appointments for ophthalmology a year, with an approximately 33% increase over...

The Worshipful Company of Spectacle Makers rewards early career research

16 October 2024 | research, awards, opportunities, optometry, opticians, glaucoma, retina, AI, OCT
The Worshipful Company of Spectacle Makers (WCSM) this week announced the winners of its annual bronze medal award competitions for vision research. Both the winning submissions demonstrated models for earlier diagnosis of significant eye disease and have the capacity to...

Novel retinal pigment metric tackles bias in AI models

25 February 2025 | AI, oculomics, Moorfields, research, equality, retinal pigment score, RPS, UCL, diversity
Researchers have developed an innovative metric for objectively classifying pigmentation in a retinal image, rather than using subjective social constructs like ethnicity or other demographic variables, as is currently the case when building health datasets. Called the Retinal Pigment Score...

First medical AI model with globally representative data

22 September 2025 | NHS, Medical AI, Eye Images, Retina, UCL, ophthalmology
Quest to build the first medical AI foundation model with globally representative data. A research consortium of over 100 study groups in more than 65 countries has launched the Global RETFound initiative, a collaborative effort to develop the first globally...