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Simulated intravitreal injection training – the way forward

1 December 2018 | | Retina / Uvea / Vitreous
Simulated surgical training is now recommended in the training curricula of all ophthalmologists in the United Kingdom [1]. Simulated training allows for familiarisation with a procedure, exercises the discipline of repetition, allows the resolution of technical difficulties and enables refinement...

Renewed momentum in ocular gene and cell therapy, broadening application to chronic disease

5 February 2020 | | Ophthalmology, Retina / Uvea / Vitreous
Gene and cell therapies offer the prospect of ground-breaking new avenues for the treatment of diseases, reflected in a renewed explosion of interest and investment in retinal gene therapy. Rod McNeil reports recent clinical trial readouts across a diverse range...

Burning vision: vision loss from misuse of ‘toy’ laser pens in children

1 April 2014 | | Cornea / External Eye Disease
A case series of five children with macular burns due to the misuse of novelty laser products, purchased online or abroad, was undertaken at the Royal Hallamshire Hospital and The Children’s Hospital, Sheffield [1]. All patients were from the Sheffield...

Headaches in ophthalmology (part 2)

1 December 2018 | | Ophthalmology, Neuro-Ophthalmology
Ophthalmologists see a large number of patients with headaches or facial pain in the ophthalmic outpatient clinics or in emergency clinics. Over two articles, I will discuss several causes of headaches, ocular manifestations and proposed management and referral options. It...

A paediatric case of central retinal artery occlusion following antibiotics and decompression surgery for orbital cellulitis

3 October 2022 | | Ophthalmology, Paediatric Ophthalmology / Strabismus
Orbital cellulitis is an ophthalmic emergency that warrants urgent management in the hospital setting [1]. This occurs more frequently in the paediatric population where it is often secondary to sinus infections. Delay in treatment could result in severe complications including...

Macular imagery: observing the visual sensations pre- and post-Jetrea injections

25 September 2021 | | Ophthalmology, Retina / Uvea / Vitreous, ONLINE EXCLUSIVE ARTICLES
A 63-year-old woman, a professional painter, was diagnosed with vitreomacular traction (VMT) in 2017. She had a history of metamorphopsia, drop in visual acuity (VA) in the left eye (6/6 in the RE; 6/18 in the LE), foveal vitreomacular traction...

Diabetic retinopathy screening in Belize: a country’s journey towards reducing blindness from DR

1 February 2019 | | Retina / Uvea / Vitreous, Ophthalmology
The rise of diabetes mellitus (DM) and its complications is a public health concern in the Caribbean. The Caribbean Diabetic Retinopathy (DR) Programme, managed by the London School of Hygiene & Tropical Medicine (LSHTM) and funded by the Queen Elizabeth...

Possible COVID-19 related maculopathy

5 April 2022 | | Ophthalmology, Imaging, Retina / Uvea / Vitreous, COVID-19
COVID-19 is being investigated as a potential cause for various ocular diseases, with growing evidence of related retinal vascular changes, that vary from isolated cotton wool spots and retinal haemorrhages to retinal vascular occlusions [1.2]. COVID-related macular affection has also...

The fragile p-value

5 October 2020 | | Ophthalmology
Abdus Samad Ansari explores the limitation of the p-value and the application of the fragility index in clinical trials. Clinical trials and tribulations? The restoration of vision or more purely the gift of sight is an aspect of care that...

Exploiting nature’s randomised trials of eye disease

1 December 2022 | | Ophthalmology, Genetics
Confounding and reverse causation in observational ophthalmic epidemiology Traditional observational studies are inherently limited in establishing a causal effect of an exposure on an outcome of interest. One fundamental limitation is confounding, whereby causation is incorrectly attributed to a third...

Can OCT predict Alzheimer’s disease?

5 February 2020 | | Ophthalmology, Optometry, Imaging
Simerdip Kaur takes a look at the latest ophthalmology-related news stories and asks which are based on facts and which are ‘fake news’. Headline: Can OCT predict Alzheimer’s disease? In 1986 Hinton et al. demonstrated evidence of optic nerve degeneration...

A window to 2024 and beyond?

3 April 2024 | | Ophthalmology
The connection between the eye and systemic diseases has been acknowledged for millenia. Historical records suggest that ancient civilisations had some understanding of the eye’s significance beyond its primary function in vision. For instance, in ancient Egypt, the ‘Eye of...