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Retinal nerve fibre layer thickness in migraine

2 February 2024 | | Paediatric Ophthalmology / Strabismus
The aim of this study is to evaluate retinal nerve fibre layer (RNFL) thickness changes in children with migraine compared to healthy controls and analyse RNFL changes dependent on type of migraine. This was an observation case control study of...

Natural history of optic nerve head drusen in a paediatric population

2 February 2024 | | Paediatric Ophthalmology / Strabismus
A retrospective case notes review is presented focusing on children diagnosed with optic nerve head drusen over an eight-year period. Inclusion criteria included cases coded for optic nerve head drusen and / or pseudopapilledema. The aim of the study was...

Structural effects of migraine on the retina

1 June 2015 | | Neuro-Ophthalmology | Migraine, retinal nerve fibre layer thickness, spectral-domain optical coherence tomography
Migraine is a common, chronic, multifactorial neuro-vascular disorder typically characterised by recurrent attacks of disabling headache and autonomic nervous system dysfunction (migraine without aura). Up to one third of patients also have neurological aura symptoms (migraine with aura). The objective...

Choroidal thickness in ocular sarcoidosis by OCT measurement

1 December 2014 | | Retina / Uvea / Vitreous | Choroidal thickness, enhanced depth imaging optical coherence tomograph, quiescent phase, sarcoidosis, uveitis
This is the first study to evaluate the choroidal thickness in patients with ocular sarcoidosis during the quiescent phase using enhanced depth imaging optical coherence tomography (EDI-OCT) and comparing with normal subjects. Ocular sarcoidosis may affect the choroidal circulation (occlusive...

Spectral domain OCT vs. confocal scanning laser ophthalmoscope in measuring RNFL thickness

1 June 2014 | | Ophthalmology | Cirrus optical coherence tomography, Heidelberg retinal tomograph 3, retinal nerve fibre layer thickness
The aim of this prospective study was to compare the retinal nerve fibre layer thickness (RNFL) measurements obtained from the Cirrus optical coherence tomography (spectral domain OCT) with the Heidelberg Retinal Tomograph 3 (HRT3, confocal scanning laser ophthalmoscope). Eighty-eight normal...

Features, treatment and prevention of conjunctival inclusion cysts

10 May 2024 | | Paediatric Ophthalmology / Strabismus
Conjunctival inclusion cyst is a rare complication of strabismus surgery and generally develops at the point of muscle reattachment, caused by implantation of conjunctival epithelium. The authors aimed to determine the rate of its development after strabismus surgery and consider...

Upper eyelid ulceration as a presenting sign of frontal sinus mucocele

3 October 2022 | | Ophthalmology
Introduction A sinus mucocele is an epithelium-lined sac filled with mucus and desquamated epithelium. It forms secondary to inflammatory processes that occur in a sinus with an obstructed ostium. Predisposing conditions include previous trauma, surgery, tumours, anatomical abnormalities, and chronic...

Ocular manifestations of multiple sclerosis: an overview

1 December 2022 | | Ophthalmology, Genetics
Multiple sclerosis (MS) is an autoimmune demyelinating disease of the central nervous system (CNS), in which there is dissemination of lesions in time (two or more clinical events) and space (multiple lesions seen on brain and spinal imaging). The pathophysiology...

Lancet Commission calls for global action on blindness

29 March 2021 |
The Lancet Global Health Commission on Global Eye Health highlights the changing nature of the issues facing eye health professionals worldwide.

Renewed momentum in ocular gene and cell therapy, broadening application to chronic disease

5 February 2020 | | Ophthalmology, Retina / Uvea / Vitreous
Gene and cell therapies offer the prospect of ground-breaking new avenues for the treatment of diseases, reflected in a renewed explosion of interest and investment in retinal gene therapy. Rod McNeil reports recent clinical trial readouts across a diverse range...

Do steroids prevent progression to proliferative diabetic retinopathy (PDR)?

1 February 2017 | | Retina / Uvea / Vitreous
There is continuing debate on the merits of pan-retinal photocoagulation (PRP) for severe pre-proliferative and proliferative DR versus the newer therapies that inhibit vascular endothelial growth factor (VEGF). This has been hotly debated [1] following the publication of findings from...

Learnings and trends in the management of open-angle and angle-closure glaucoma

1 August 2017 | | Glaucoma
To be truly disruptive, newer technologies need to offer a quality of life benefit over medication to a broad population of glaucoma sufferers. Evidence and converging trends in medical and surgical management of glaucoma were explored in counterpoint discussions and...