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Monocular eye closure following treatment of intermittent exotropia

The purpose of this study was to evaluate the short- and long-term status of monocular eye closure after surgical treatment of intermittent exotropia and to determine whether the status at short-term postoperative follow-up duration remains or can change after long-term...

Likelihood of developing multiple sclerosis after optic neuritis diagnosis

Optic neuritis (ON) is a relatively common cause of acute optic neuropathy in young patients which often presents as the first sign of multiple sclerosis (MS). There is a lack of evidence around the factors that are associated with the...

Repeat corneal collagen cross-linking after failure of primary cross-linking (CXL) in keratoconus

This is a 10-year, retrospective, patients record review from Leeds, UK. Twenty-one eyes had repeated CXL and the mean interval between primary and repeat CXL was 47.1 months. Twenty (95%) eyes stabilised after repeated CXL at a mean follow-up of...

Adjunct amniotic membrane during enucleation for retinoblastoma to prevent implant exposure

Amniotic membrane (AM) has potential for treatment of retinoblastoma (RB) patients with contracted sockets after enucleation. The authors present their experience of AM with enucleation for patients with RB after chemotherapy in this retrospective study of 100 eyes of 107...

Changes in extraocular muscle after the Faden procedure – animal histopathology model

The authors studied the histological changes in the anterior part of the posterior fixation suture including the myoscleral junction, after the Faden operation in eight rabbits. The Faden operation was undertaken in one eye and the fellow unoperated eye served...

The last three patients: dermatology (Patient Three)

For the third and final reflection in this series (see Part 1 and Part 2), Professor Jonathan Rees recounts his experience of a patient with cancer who was failed by the NHS, and how their inadequate treatment illuminates some issues...

Boston type I keratoprosthesis for limbal stem cell deficiency

Boston type I keratoprosthesis (KPro) long-term outcomes were compared in patients with and without limbal stem cell deficiency (LSCD) in this retrospective study. In the 11 year period 68 procedures were performed in individuals with LSCD, and 105 procedures in...

Risks factors for graft preparation failure in DMEK

Diabetes mellitus (DM) makes it more difficult to prepare descemet membrane epithelial keratoplasty (DMEK) grafts due to the ‘stickiness’ of Descemet’s membrane. This retrospective study examined a classification system, where donors were scored points according to their DM related risk...

OCTA use in CNV associated with CSR

The aim of this study was to assess the rate of choroidal neovascularisation (CNV) in chronic central serous chorioretinopathy (CSR) patients with flat irregular pigment epithelial detachments (PEDs) by optical coherence tomography angiography (OCTA). Data of all consecutive patients with...

Acute retinal necrosis: an Indian experience

The authors of this retrospective study aimed to provide clinical outcomes in 62 eyes of 53 patients presenting with acute retinal necrosis. All eyes received intravenous acyclovir (10mg/kg tds) for 7-10 days followed by oral antiviral therapy (valaciclovir 1g tds...

Mitomycin C versus 5-FU as an adjunctive treatment for trabeculectomy

Antifibrotic agents are used during trabeculectomy (TRAB) to improve long-term surgical success by reducing fibrosis of subconjunctival and episcleral tissue. The purpose of this meta-analysis was to directly compare the efficacy and safety of the two most frequently used antifibrotic...

Effect of cataract surgery on inflammation control and vision in uveitis patients

This retrospective longitudinal study from Moorfields, London, UK compared uveitis recurrence rates and vision loss in 309 eyes of uveitis patients post cataract surgery to 300 control uveitis patients. Cataract is a common complication associated with uveitis and leads to...