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British Journal of Ophthalmology cover image.

Long-term effect of YAG LPI on corneal endothelium in PACS

4 August 2021 | | Cornea / External Eye Disease
This is a single-centre randomised controlled trial of 875 patients with bilateral primary angle closure suspect (PACS) who received YAG laser iridotomy (LPI) prophylactic treatment in one eye randomly and the fellow eye served as control over 72 months. Central...

G-CSF intravitreal injections for NAION: a pilot study

5 April 2022 | | Neuro-Ophthalmology | Anterior ischemic optic neuropathy, Granulocyte colony-stimulating factor, Intravitreal injection, Neuroprotection, Optic atrophy
In rodent models with anterior ischemic optic neuropathy (AION), granulocyte colony-stimulating factor (G-CSF) confers a neuroprotective effect on retinal ganglion cells (RGCs) via anti-apoptotic and anti-inflammatory processes. This prospective study investigated the efficacy of intravitreal injection of G-CSF for the...

Comparison of SIA from femtosecond laser and manual CCIs for cataract surgery

1 December 2018 | | Cataract and Refractive
This study group compared the differences in surgically induced astigmatism (SIA) vector, flattening effect, torque and wound architecture following both femtosecond laser and manual clear corneal incisions (CCIs). A double-armed, randomised, prospective case series was conducted. Cataract surgery was performed...

Are retinal vein occlusions seasonal? And if so why might that be?

1 June 2015 | | Retina / Uvea / Vitreous | Central retinal vein occlusion, Sweden, incidence, seasonality, vitamin D
Some studies have reported a strong seasonal pattern to central retinal vein occlusion (CRVO) occurrence with a peak in January, but other studies have failed to replicate this finding. The authors sought to determine data for Stockholm’s seasonal variation in...

Intravitreal injection related endophthalmitis

1 April 2015 | | Retina / Uvea / Vitreous | Age-related macular degeneration (AMD), endophthalmitis, intravitreal injection, post-injection complications, vascular endothelial growth factor (VEGF)
This article reviews the incidence, clinical findings, risk factors, management and visual outcomes in intravitreal injection related endophthalmitis. Incidence of this complication is reported to be in the range of 0.038% to 0.065% (1 in 2000-3000 injections). Patients present typically...

The challenge of chorioretinal folds in virtual eye clinics

3 June 2024 | | Retina / Uvea / Vitreous, Orbit
Chorioretinal or choroidal folds are parallel striations involving the retina, retinal pigment epithelium (RPE), Bruch’s membrane, and inner choroid [1]. They can arise from compressive stress on these layers, and their presence often serves as a diagnostic marker for underlying...

Feb/Mar 2018 Quiz

1 February 2018 | Cataract and Refractive, Cornea / External Eye Disease, Genetics, Glaucoma, Imaging, Neuro-Ophthalmology, Ocular Pathology and Oncology, Oculoplastics, Ophthalmology, Optometry, Orbit, Paediatric Ophthalmology / Strabismus, Retina / Uvea / Vitreous, AMD, Emergency Ophthalmology
History A 48-year-old farmer with gradual worsening vision in her only eye was referred by her optician. She had recently moved to the UK and required an interpreter during consultation. She seemed to have had vision problems since childhood. Although...

Aug/Sep 2014 Quiz 1

1 August 2014 | | AMD, Cataract and Refractive, Cornea / External Eye Disease, Emergency Ophthalmology, Genetics, Glaucoma, Imaging, Neuro-Ophthalmology, Ocular Pathology and Oncology, Oculoplastics, Ophthalmology, Optometry, Orbit, Paediatric Ophthalmology / Strabismus, Retina / Uvea / Vitreous
History A 50-year-old female with a history of smoking, weight loss and cough presents to the ophthalmology clinic with a distorted pupil. Examination reveals a mass on the surface and within the iris (see Figure 1). The ophthalmologists decide to...

The results of the last survey Jun23

5 June 2023 | | Ophthalmology
*Please be aware that this data does not form part of a peer reviewed research study. The information therein should not be relied upon for clinical purposes but instead used as a guide for clinical practice and reflection. I continue...

Cyanoacrylate nail glue accidentally instilled into the eye instead of eye drops

1 April 2016 | | AMD, Cataract and Refractive, Cornea / External Eye Disease, Emergency Ophthalmology, Genetics, Glaucoma, Imaging, Neuro-Ophthalmology, Ophthalmology, Ocular Pathology and Oncology, Oculoplastics, Optometry, Orbit, Paediatric Ophthalmology / Strabismus, Retina / Uvea / Vitreous
Three hundred thousand cataract operations take place each year in the UK alone and each patient will receive a four week course of drops in order to cover them for any postoperative inflammation or infection. Accidental instillation of cyanoacrylate glue...

Strange Sequelae Succeeding ‘Surfer’s Eye’

1 February 2014 |
Ophthalmologists in the UK are relatively infrequently faced with a patient requesting surgery for a pterygium. This condition is more common where ultraviolet exposure is greater, especially if coupled with activities associated with ocular surface irritation. For this reason, a...

How a calcified Soemmerring ring was removed from the vitreous cavity when the cutter and forceps failed to do so

1 June 2018 | | Retina / Uvea / Vitreous
Know’st thou the land where lemon-trees do bloom,And oranges like gold in leafy gloom; A gentle wind from deep blue heaven blows, The myrtle thick, and high the laurel grows? ‘Tis there! ‘tis there, O my beloved one, I with...