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Incidence of ocular myasthenia gravis and risk factors for conversion to generalised disease
This population based retrospective cohort study evaluates the incidence of ocular myasthenia gravis (OMG) as well as risk factors for transformation to generalised myasthenia gravis (GMG). Sixty-five patients (40 male and 25 female) with newly diagnosed with myasthenia gravis (MG)...
Predictors of IOP reduction after SLT
The aim of this study was to identify predictors of intraocular pressure reduction following selective laser trabeculoplasty (SLT) in patients with primary open-angle glaucoma, who are already taking maximally tolerated IOP-lowering medication and need further IOP reduction. In this prospective...
Diabetic retinopathy and body fat distribution and adipokine secretion in type 2 diabetics
The major risk factors for diabetic retinopathy (DR) in patients with diabetes are poor glycaemic or blood pressure control, duration of diabetes and nephropathy related to the severity of DR. Several studies suggest that DR is associated with visceral fat...
Eyelid nodule outcomes
Idiopathic facial aseptic granuloma (IFAG) is a recently defined paediatric dermatology disorder. This study presents the clinical outcomes of children with IFAG nodules on their eyelids with or without facial nodules and aim to compare the outcomes with those presenting...Psychiatric Consequences of Ophthalmic Disease
In part two of this series on ophthalmology and psychiatry, the authors will cover the possible psychiatric consequences of ophthalmic disease. The following conditions will be discussed: a. Black patch psychosis b. Psychological state in blindness c. Phobias in the...
Use of international interocular difference thresholds for optic neuritis diagnosis in clinical practice
Multiple sclerosis (MS) is the most common non-traumatic cause of disability in young people, and visual symptoms can be the initial manifestation in up to 20% of cases. Retinal examination can be helpful in making the correct diagnosis. The latest...
Topical cyclosporine A 0.05% for recurrent anterior uveitis
This is a retrospective case-crossover study conducted by reviewing medical charts of patients treated for recurrent anterior uveitis between 2002 and 2011 at the Kellogg Eye Centre by one cornea specialist. The demographics, episodes of anterior uveitis, severity of episodes...Gene therapy for inherited retinal disease: the Manchester Ocular Gene Therapy Group MDT service
The authors describe the process set up in Manchester for the optimum delivery and assessment of a new gene therapy treatment for patients with RPE65 IRD. Inherited retinal dystrophies (IRDs) are the second commonest cause of severe visual impairment in...Refraction planning in cataract: avoid creating an unhappy patient
“It is much more important to know what sort of a patient has a disease than what sort of a disease a patient has.” William Osler The focus of this paper is the prevention of an unhappy patient following cataract...
Assessment and management of dry eye disease
This paper is an update on the assessment and management of dry eye disease (DED). According to the second International Dry Eye Workshop 2017, “Dry eye is a multifactorial disease of the ocular surface characterised by a loss of homoeostasis...
