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Rituximab as an immunosuppression treatment for thyroid eye disease
Thyroid eye disease is traditionally treated with high dose glucocorticosteroids and surgical orbital decompression, where responses are often inadequate. This medical treatment is centred around symptom control and reduction of thyroid hormone synthesis, not immunosuppression. Rituximab is an anti-CD20 monoclonal...
Association between neuro-ophthalmology signs and chronic ataxia in children
Neuro-ophthalmological signs (N-OS) occur commonly in children with chronic ataxia. This study describes the N-OS and their frequencies, in general and by specific disease aetiology in paediatric patients with chronic ataxia. In total, 184 patients under the age of 17...
Visual outcomes, visual fields and optical coherence tomography in paediatric craniopharyngioma
This study reviews the visual outcomes of ten patients under the age of 18 years with craniopharyngioma. The paper also reviews the correlation between visual field (VF) testing and optical coherence tomography (OCT) examination and evaluates the role of OCT...
Meibomian gland alteration in patients with primary chronic dacryocystitis: An in vivo confocal microscopy study
Chronic dacryocystitis affects tear film functionality and can predispose to ocular surface disease, however the specific effect of chronic dacryocystitis on meibomian gland function has not been studied. This group therefore performed in vivo confocal microscopy in 28 patients’ eyes...
Systemic rituximab immunotherapy in the management of primary ocular adnexal lymphoma single institutional experience
Ocular adnexal lymphomas constitute 2% of all non-Hodgkin’s disease and 5-15% of all extranodal lymphomas and are usually localised, low-grade and of B-cell origin. This opens them up to potential treatment with a systemic monoclonal antibody-based drug (rituximab) directed at...
Lower postoperative scar height is associated with increased postoperative trichiasis one year after bilamellar tarsal rotation surgery
Bilamellar tarsal rotation has been a key component of the WHO SAFE approach to blindness from trichiaisis (surgery, antibiotics, facial hygiene, environment). The World Health Organisation (WHO) manual describes the procedure as a full thickness blepharotomy placed 3.0mm above and...
Ointment related granulomas post-blepharoplasty
This is a retrospective review of eight patients who developed granulomatous masses after lower lid blepharoplasty. All patients had sutureless bilateral trans-conjunctival surgery, and lubricating ointment was instilled into the inferior fornix postoperatively for two days. Painless lower lid masses...
Evaluating ocular motor functions
Traditionally orthoptists are specialised in assessing ocular motor disorders. This article introduces the ocular motor score as a new clinical tool for screening and follow-up for children and young adults. The protocol consists of 15 tests such as stereoacuity, strabismus,...
Prism cover test variances
The purpose was to establish the inter-examiner variability and agreement between more than two examiners assessing children and adult patients. The study involved four experienced examiners. The alternate prism cover test (APCT) was conducted at near and distance in 41...
Computerised tomography in ocular trauma patients
Ocular trauma can be common in military settings. This retrospective study looked into the relationship between the clinical effects of acute ocular and orbital blast trauma with the findings on computerised tomography (CT). This was a consecutive case series of...
Uveitis in the elderly
This study from Turkey evaluated the causes and clinical characteristics of uveitis in elderly patients. Data from 90 eyes of 68 patients aged 60 years and older were reviewed. Anterior uveitis was present in 75% (33% of these had keratouveitis),...
