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The clinical spectrum of albinism
The authors sought to examine clinical correlates that may be related to foveal development in albinism with an aim to qualitatively describe the phenotype spectrum of albinism. Binocular best corrected visual acuity ranged from 20/20 to 20/80. Best corrected visual...
MR- vs. LR+ for divergence insufficiency
A retrospective study was conducted to compare the efficacy of medial rectus recession and lateral rectus resection as surgical interventions for divergence insufficiency in 18 patients. These were cases of non-neurological cause. Two patients in each group required postoperative adjustment....
Computerised visual acuity measurements in AMD
The aims of this study were to investigate whether half-letter width spacing in COMPlog algorithms had an adverse effect on agreement in patients with AMD with the ETDRS chart. Fifty adult participants with AMD took part with a median age...
AMD and visceral fat and pro-inflammatory factors
Several large studies have shown a positive relationship between age-related macular degeneration (ARMD) and high body mass index. The waist-hip ratio is also associated with development of early AMD. Visceral fat has a pro-inflammatory effect, which means it has an...
Cyclosporine A and pterygium fibroblasts
The matrix metalloproteinases (MMP) are a family of structurally related zinc-dependent extracellular matrix degrading proteinases that have been implicated in facilitating the migration and growth of pterygia. Both MMP- 3 and MMP-13 were found to be overexpressed in the fibroblasts...
Comparison of methods of central corneal thickness measurement in glaucoma
This prospective study was done to compare the accuracy and reproducibility of central corneal thickness measured by hand-held and disc-mounted ultrasound pachymeter in glaucoma patients. Sixty-five patients were included in the study. Patients with corneal diseases, corneal astigmatism >3 diopters...
Rituximab as an immunosuppression treatment for thyroid eye disease
Thyroid eye disease is traditionally treated with high dose glucocorticosteroids and surgical orbital decompression, where responses are often inadequate. This medical treatment is centred around symptom control and reduction of thyroid hormone synthesis, not immunosuppression. Rituximab is an anti-CD20 monoclonal...
Association between neuro-ophthalmology signs and chronic ataxia in children
Neuro-ophthalmological signs (N-OS) occur commonly in children with chronic ataxia. This study describes the N-OS and their frequencies, in general and by specific disease aetiology in paediatric patients with chronic ataxia. In total, 184 patients under the age of 17...
Visual outcomes, visual fields and optical coherence tomography in paediatric craniopharyngioma
This study reviews the visual outcomes of ten patients under the age of 18 years with craniopharyngioma. The paper also reviews the correlation between visual field (VF) testing and optical coherence tomography (OCT) examination and evaluates the role of OCT...
Systemic rituximab immunotherapy in the management of primary ocular adnexal lymphoma single institutional experience
Ocular adnexal lymphomas constitute 2% of all non-Hodgkin’s disease and 5-15% of all extranodal lymphomas and are usually localised, low-grade and of B-cell origin. This opens them up to potential treatment with a systemic monoclonal antibody-based drug (rituximab) directed at...
Lower postoperative scar height is associated with increased postoperative trichiasis one year after bilamellar tarsal rotation surgery
Bilamellar tarsal rotation has been a key component of the WHO SAFE approach to blindness from trichiaisis (surgery, antibiotics, facial hygiene, environment). The World Health Organisation (WHO) manual describes the procedure as a full thickness blepharotomy placed 3.0mm above and...
