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4020 results found

BT outcomes under open versus closed sky technique

This retrospective study compared open versus closed sky BT injection techniques without electromyography (EMG) control in 135 patients (31 open sky and 104 closed). Patients were aged 1-50 years for open sky and 2-34 years for closed. There was a...

Brolucizumab in age-related macular degeneration, HAWK Study

The aim of the study was to collect additional data on efficacy and safety of brolucizumab 6mg intended for commercialization in age-related macular degeneration (AMD) (with an increase in pH and decrease in polysorbate concentration). The HAWK Study was a...

Multidrug-resistant keratitis: challenging yet manageable

This is a retrospective review of all patients’ records from a tertiary referral centre in India from January 2018 to December 2019, who had corneal scrapings for direct smear and culture sensitivity. Those cases where the organisms were diagnosed to...

New management algorithm for acute post cataract endophthalmitis

In this study, the authors aimed to establish an objective algorithm for recommending urgent pars plana vitrectomy (PPV) to help improve visual outcomes in the current era of clear corneal-incision phacoemulsification and small gauge PPV. This study examined 150 cases...

Retinal nerve fibre layer thickness in migraine

The aim of this study is to evaluate retinal nerve fibre layer (RNFL) thickness changes in children with migraine compared to healthy controls and analyse RNFL changes dependent on type of migraine. This was an observation case control study of...

Combined in-office and home-based eccentric viewing training for central vision loss

This retrospective study aimed to investigate the effectiveness of an eccentric viewing training (EVT) programme delivered in a real-world setting (home exercises) by combining a traditional EVT technique with biofeedback training using microperimetry. The authors investigated potential relationships between visual...

OCTA optic disc measurement differences between glaucoma and pituitary macroadenoma

This prospective case-control study aimed to assess the potential of optical coherence tomography (OCT) and OCT angiography (OCTA) in distinguishing between glaucoma and pituitary macroadenoma based on optic disc appearance. Thirty-one patients (23 with glaucoma, eight with pituitary macroadenoma) were...

Choice of diclofenac or corticosteroids for strabismus surgery

This systematic review was undertaken to analyse the available data on various corticosteroids and diclofenac to determine the most effective postoperative anti-inflammatory agent for patients with strabismus. Twenty-five studies were identified from 1997–2021 and a total of eight met the...

Is thrombolytic treatment warranted for central retinal artery occlusion?

Central retinal artery occlusion (CRAO) is a subtype of acute ischaemic stroke which results in severe visual loss. Acute CRAO is equivalent to a brain acute ischaemic stroke (AIS), as the obstruction of the central retinal artery (CRA) causes end-organ...

MPH treatment effect in ADHD on choroidal vascular index

In this study the authors aimed to investigate the choroidal vascular index (CVI) in treatment-free children with ADHD, children regularly taking methylphenidate (MPH) and healthy controls. This was a prospective cross-sectional study of 52 patients with newly diagnosed ADHD, 46...

Use of Leflunomide as a treatment for paediatric chronic uveitis

Leflunomide is a disease modifying anti-rheumatic drug approved for treatment of rheumatoid arthritis and psoriatic arthritis in adult patients. This study reports five illustrative case reports of children using Leflunomide as an adjunct treatment with anti-tumour necrosis factor (TNF) agents...

Ahmed and Baerveldt glaucoma drainage implant outcomes

This study reports the surgical outcomes of both the Ahmed (AGV) and Baerveldt (BGI) glaucoma drainage implants in a cohort of patients with primary congenital glaucoma over a long follow-up in a single tertiary centre. This was a retrospective study...