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Boosting key protein in eye cells could prevent age-related vision loss, international team finds

Increasing the levels of a key protein in the cells at the back of the eye could help protect against the leading cause of vision loss among older adults, finds a new discovery made by researchers from the UK, US, Germany and Australia.

MRI in anisometropic amblyopia

This study recruited patients with anisometropic amblyopia in the right eye and without strabismus. This allowed the authors to reduce the effort exerted in cortex activities by different amblyopic eyes. They used whole brain analysis to find the differences between...

Case report of Leber hereditary optic neuropathy (LHON)

This case report presents a 74-year-old male patient who developed LHON, with a previous diagnosis of bilateral macular holes. LHON occurs predominantly in healthy young men and onset in older age ranges increases the likelihood that the patient will have...

More sensitive visual acuity test for age-related macular degeneration

Age-related macular degeneration (AMD) is the leading cause of blindness in the developed world. Primarily associated with ageing, genetic factors and lifestyle choices such as smoking also play a contributory role. Patients with early AMD, characterised by the development of...

Ocular motor score in spastic hemiplegia

The authors aimed to assess the oculomotor functions in children with spastic hemiplegia (SH) caused by different brain pathologies and evaluate the results obtained by the ocular motor score (OMS). The study included 34 children with a median age of...

Charles Bonnet Syndrome emerges from the shadows

There has been a ground-breaking response to the online Charles Bonnet Syndrome Patient Information event on 16 November.

All systems go for Oriel - final approval granted to make new centre a reality

Plans for Oriel, a new state-of-the-art eye care, research and education centre, have been given the green light.

Embedding EMR for a complete transformation in user experience

Informatics and IT projects in the NHS have a history of being over budget, delivered late and not fulfilling the design brief. “But it doesn’t have to be that way,” believes Chris Canning, Consultant Ophthalmologist and Chief Clinical Information Officer...

Topical atorvastatin for dry eye and blepharitis

Dry eye is a very common problem with 20% of the population affected and is frequently associated with blepharitis (DEB), which has an over prevalence of about 40%. The aim of this study was to evaluate a topical atorvastatin formulation...

Stereotactic radiotherapy for polypoidal choroidal vasculopathy

Polypoidal choroidal vasculopathy (PCV) is a variant of neovascular AMD. It is a disease of choroidal vasculature characterised by abnormal branching vascular network with aneurysmal dilatations (polyps). Features of PCV include pigment epithelial detachments (PED), subretinal fluid (SRF) accumulation and...

Diary from my elective: a Parisian experience

The author explains how a research institute’s dedication to multidisciplinary collaboration helped him to discover a passion for academic ophthalmology. The elective aspect to the final year of a medical degree, through its change of scenery and immersion into another...

MicroRNAs in cataract

In an ageing population cataract formation is one of the leading causes of blindness. Cataracts are caused by a failure to clear accumulating aggregated proteins in the lens. MicroRNAs are small non-coding transcripts which bind to specific mRNAs acting at...