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RaScaL Study

The RaScaL study was a six month, single-centre, controlled, prospective phase I/II study in which subjects with diabetic macular oedema (DME) and associated peripheral nonperfusion on ultrawide-field fluorescein angiography (UWFA) were randomised to: (1) study arm: ranibizumab (0.5 mg) injection...

Retinoblastoma management update (part 2): treatment, screening and surveillance, long-term follow-up and new developments

Retinoblastoma treatment requires significant multidisciplinary input, but early detection through raising awareness remains key to improving outcomes. In the second article of a two-part series, Manoj Parulekar discusses retinoblastoma management, screening and research. This article has been published in two...

Risk factors and management for postoperative complications in strabismus surgery

This retrospective cohort study examined 1273 patients, comprising 1035 cases of exotropia and 238 cases of esotropia, with a minimum 18-month follow-up after strabismus surgery. Baseline demographics, age at surgery, pre / postoperative visual acuity, and deviation were included. Complications...

Initiatives in macular service provision

A report from Monitor in October 2015 identifies good practices that will realise most of the potential productivity gain in elective care available to NHS hospitals. These include: stratifying patients by risk and creating low-complexity pathways for lower-risk patients (tailoring...

What can we learn from Jimmy McGill?

A few months ago, my eldest son got me interested in a Netflix series called “Better Call Saul”. This is a spin-off from another series called “Breaking Bad”, although I confess to not having seen any of those episodes as...

Four rectus muscle surgery for infantile nystagmus syndrome

The authors present a case report of infantile nystagmus syndrome (INS) with abnormal head posture (AHP) of face turn, head tilt and chin depression with a single-step surgery of all four horizontal rectus muscles. The case was a 26-year-old male...

Refractionist’s shoulder?

After hearing the letter-box, I walked to the front door and stooped down to collect my latest edition of Eye News. I winced. Still, at least it would give me something to pass the time on this, my first day...

Should we work together to identify congenital nasolacrimal duct obstruction and otitis media?

The authors present a retrospective medical notes review. The aim of the study was to establish how common tympanostomy tube (T-tube) insertion is in children needing probe and intubation (P&I) for congenital nasolacrimal duct obstruction (CNLDO). All cases of CNLDO...

Optic nerve swelling – your survival guide (part 1)

Assessment of optic nerve appearance and functions is a daily routine in neuro-ophthalmology. Following a recent high profile court case there has been a significant increase in the amount of referral to ophthalmology departments to assess the optic nerve and...

Mucormycosis: In conversation with Dr Deepak Haldipur and Dr Aditya Moorthy

COVID-19 has ravaged the world in the past 18 months. The second wave in many countries was deadlier than the first. Mucormycosis, infamously labelled ‘the black fungus’ has affected some countries, such as India, in epidemic proportions within this COVID...

Medial rectus spontaneous reattachment after surgery

The authors report necropsy findings following free tenotomy of the medial rectus (MR) muscle in six postnatal monkeys. Bilateral MR tenotomy was performed producing alternating exotropia of 30-70 degrees with no adduction beyond primary position. Over follow-up, all showed reduction...

Ranibizumab safety in pregnancy

Vascular endothelial growth factor (VEGF) plays a pivotal role during pregnancy, and systemic anti-VEGF administration during this period should thus be avoided. VEGF is expressed in multiple embryonic and foetal tissues during development, with the highest levels found in the...