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Autophagy in lens mitochondria loss
The lens consists of a monolayer of epithelial cells that overlies fibre cells that differentiate from epithelial cells at the equator. While developing, fibre cells need mitochondria to provide energy, as they mature they lose these and other organelles to...
EDTA chelation for band keratopathy
The authors describe a retrospective analysis of 89 eyes from 72 patients who underwent ethlenediamine tetra-acetic acid (EDTA) chelation for band keratopathy. The ratio of R:L eye was 41:48. The mean age was 71 years (range 18-93 years). Thirty-two out...Cementing a VISION 2020 LINK partnership between Blantyre and Liverpool – building capacity for DR services alongside research
Malawi is a small land-locked country in eastern Africa with a growing population of over 17 million people. About 45% of the population is aged 14 or under; only 5% are aged 60 or over. The gross national income per...Sustainability in eyecare: Intraocular gases and the climate emergency
In 2020 the NHS became the first national health system to commit to delivering ‘net zero’ carbon emissions by 2040. The author investigates how the impact of ophthalmic surgery can be reduced. Medical gases have been used in ophthalmic surgery...
ROP anti-VEGF treatment review
The purpose of this review was to consider data relating to risks and benefits of the use of anti-VEGF treatment for retinopathy of prematurity (ROP) over the past five years of 2015-2020. Ocular benefits include treatment of aggressive posterior ROP,...
Effects of blood donation on the physiology of the eye
Hypovolaemia is a state of decreased blood volume, the reduction of which reduces tissue perfusion which may in turn lead to cellular hypoxia and end-organ damage. In blood donation, 500ml of blood is collected in ten minutes. This equates to...
Choroidal thickness in ocular sarcoidosis by OCT measurement
This is the first study to evaluate the choroidal thickness in patients with ocular sarcoidosis during the quiescent phase using enhanced depth imaging optical coherence tomography (EDI-OCT) and comparing with normal subjects. Ocular sarcoidosis may affect the choroidal circulation (occlusive...Thyroid eye disease
Thyroid eye disease (TED) is an autoimmune condition with a spectrum of signs and symptoms, usually associated with Graves’ hyperthyroidism. The diagnosis is based on history and physical examination but there are further investigations that can aid diagnosis if unclear....
Inferior oblique adherence syndrome
A case is reported of a 14-year-old with inferior oblique muscle adherence and fat adherence following unilateral inferior oblique (IO) anteriorisation. Following surgery, the patient developed consecutive esotropia, ptosis and marked limitation of laevoelevation. Forced duction test was positive for...
