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Efficacy of cyclo 1% spray
The aim of this study was to evaluate the efficacy and tolerability of cyclopentolate 1% spray in patients aged three to six years. This was a cross section parallel group study of 61 children. Thirty-one received cyclo 1% drops and...
Risk of CNV related to angioid streaks in PXE
This retrospective cross-sectional study investigated 301 patients with pseudoxanthoma elasticum (PXE) for prevalence of choroidal neovascularisation (CNV) and macular atrophy. Some patients were excluded due to missing or poor-quality imaging or the fact that they didn’t have angioid streaks, leaving...
Characteristics of Charles Bonnet syndrome in patients with neovascular AMD
This retrospective cross-sectional study aimed to characterise various aspects of Charles Bonnet syndrome hallucinations among patients with neovascular age-related macular degeneration (AMD). Five hundred and ten consecutive patients were asked a screening question to determine if they had ever suffered...
Caffeine concentration in the vitreous after drinking coffee
Caffeine is known to penetrate many bodily fluids, including the vitreous. In this prospective study, investigators measured caffeine levels in vitreous samples from patients undergoing vitrectomy and epiretinal membrane peel. Patients were divided into habitual and non-habitual coffee drinkers. One...
Effect of blue-light filtering intraocular lenses on age-related macular degeneration
This is a retrospective cohort study evaluating whether blue-light filtering (BLF) intraocular lenses (IOL) offer prophylaxis for neovascular age-related macular degeneration (nAMD). The study included 11,397 eyes of 11,397 patients with a mean age of 75.4 ±8.3 years that underwent...
Restoration of colour perception in patients with retinitis pigmentosa
This is a case series testing the feasibility of using bioelectronic retinal prostheses to partially restore colour perception in seven patients with advanced retinitis pigmentosa. Bioelectronic retinal prostheses are able to bypass degenerated photoreceptors to directly stimulate the inner retinal...
Cataract extraction and microperimetry
In this study, the authors assessed retinal sensitivity before and after cataract extraction, in an effort to understand how lens opacities may affect microperimetry results in glaucoma and macular diseases. Thirty patients awaiting cataract extraction were examined and their lens...
Can the angle of origin of the ophthalmic artery predict embolic trajectory?
A retrospective, comparative case-control study was used to test the hypothesis that a risk factor for retinal versus cerebral infarct is the angular origin of the ophthalmic artery from the internal carotid artery. The study compared one group (n=28) who...
Thalamic infarcts and the associated neuro-ophthalmic sequelae
The authors present a retrospective review of clinical and imaging data from a stroke database over a 10-year period. Of those identified as having a thalamic infarction (n=342), 40 were found to have neuro-ophthalmic sequelae (11.7%). The neuro-ophthalmic sequelae reported...
5-FU in cicatricial conjunctivitis
This is a retrospective review of 56 patients with cicatricial conjunctivitis, including 25 eyes that received sub-conjunctival injections of 25-50mg of 5-fluorouracil (5-FU) as part of their treatment. Thirty-seven patients had ocular cicatricial pemphigoid (OCP) and 19 had Stevens-Johnson syndrome...
Variability and reliability of Lea grating paddles
The authors aimed to determine interobserver variability and reliability of Lea grating paddles when assessing grating acuity in pre and non-verbal children. This was a prospective study of 31 consecutive patients; 29 pre-verbal <36 months and two with delayed speech...
