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Protecting retinal ganglion cells
Glaucoma is considered to be a heterogeneous group of conditions giving retinal ganglion cells (RGC) damage. Lowering intraocular pressure (IOP) reduces the risk of progressive RGC loss in glaucoma. Regeneration of the optic nerve has been shown to restore some...
Post hoc analysis of the CANTREAT randomised trial
CANTREAT, a Canadian multicentre two-year randomised trial compares treat and extend treatment (T&E) relative to the monthly administration of Ranibizumab in nAMD. Two-hundred and eighty-five treatment-naïve patients with nAMD were randomised to receive either a once-monthly dosing or T&E regimen...
Licence to save: a UK survey of anti-VEGF use for the eye
This comment article highlights the controversy that exists in the choice for anti-VEGF drugs used for treatment of macular oedema and wet age-related macular degeneration (AMD). Two existing licensed drugs for macular oedema are ranibizumab (Lucentis) and aflibercept (Eylea). A...
Prediction errors of formulas in optical biometers
This study was conducted retrospectively in a private practice setting. Nine formulas were compared for prediction error (postoperative spherical equivalent (SE) minus, predicted SE calculated by each formula), using two optical biometers (Lenstar – optical low coherence reflectometry (OLCR) and...
Leber’s hereditary optic neuropathy: from lab to clinic
Leber’s hereditary optic neuropathy (LHON) was the first clinically described mitochondrial disorder (1871). This article reviews the pathophysiology and clinical features of LHON with a focus on translational research. G11778A is currently the most common mutation worldwide and is associated...Evidence shows hand-holding volunteers help significantly reduce anxiety for patients undergoing eye procedure
New evidence from an evaluation carried out by Helpforce for Friends of Moorfields shows that a volunteer’s support can help patients while they have eye surgery under local anaesthetic. 94% say the support helped them feel less anxious.
Intravitreal afibercept and ranibizumab for PCV
This is a retrospective, interventional series comprising 98 eyes with polypidal choroidal vasculopathy (PCV) with the aim of comparing treatments with afibercept and ranibizumab, highlighting any differences in their efficacy. Case notes and imaging (FFA / ICG / OCT) were...
What effects do repeated Ozurdex implants have in paediatric uveitis?
The aim of this retrospective study was to assess the anatomical and functional results, as well as complications of repeated Ozurdex intravitreal implants in a paediatric (non-infectious) uveitis cohort. Twenty-two eyes (16 patients) received 35 Ozurdex implants over a six...Inverness resident leads the way with sight loss walking group
An Inverness resident, supported by a national sight loss charity, meets monthly with other blind and partially sighted locals for a wander around Inverness city centre.
25-gauge PPV for retained lens fragments
This was a retrospective study including 40 eyes of 40 patients with mean age of 78 years, 19 females and 21 males, who underwent 25-gauge pars plana vitrectomy (PPV) for retained lens fragments with a minimum of six months of...£5 million award for world-leading research facilities within new eye health centre
The Sir Jules Thorn Charitable Trust has awarded £5 million to UCL in partnership with Moorfields Eye Charity and Moorfields Eye Hospital to support Oriel – a centre for advancing eye health, opening in 2027.
