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How does cataract surgery affect eyes with wet AMD?

In this retrospective cohort study the authors’ primary objective was to assess whether cataract surgery in eyes with wet age-related macular degeneration (AMD), triggered its progression. The surgical group comprised of 40 eyes versus 42 eyes in the non-surgical control...

Endophthalmitis after intravitreal injections in France

In this nationwide, retrospective, multicentre case series, the authors looked at the incidence and characteristics of endophthalmitis after intravitreal injections of anti-VEGFs and steroids, given for a variety of posterior segment conditions (macular oedema secondary to diabetes or retinal vein...

Is there an association between dry eye disease and depression and anxiety?

Dry eye disease is a widespread ocular surface condition (prevalence 5.5-33.7%) that has been previously linked to systemic diseases, such as Sjogren, rheumatoid arthritis and more recently possibly also depression, in small population-based studies. The authors’ aim was to investigate...

Improved quality of life in children with allergic conjunctivitis and their parents with anti-allergic therapy

This prospective intervention study investigated the change in quality of life in child-parent pairs with allergic conjunctivitis (AC) on anti-allergic therapy. From September 2020 to May 2021, AC child-parent pairs and healthy child-parent pairs were recruited in Guangzhou, China. Children...

Comparison of two interferon gamma release assays (IGRA) for tuberculous uveitis

In this prospective cohort study the authors compared QuantiFERON-TB Gold In-Tube and T-SPOT.TB to evaluate their diagnostic accuracy. They enrolled 120 consecutive new uveitis presentations over a two year period in a tertiary centre. The majority were Chinese (61.3%), followed...

Intraoperative floppy iris syndrome and prevalence of intraoperative complications

Alpha-blockers (particularly of the selective type) are known to be associated with intraoperative floppy iris (IFIS) and poor dilation, which can present in various severities during cataract surgery and need to be recognised in order to avoid intraoperative complications. Methods...

Epiretinal membranes in uveitic macular oedema

Epiretinal membrane (ERM) formation in uveitic macular oedema is a fairly common structural complication of the retina. The authors describe a retrospective case series of 104 eyes of 77 patients with uveitic macular oedema from a tertiary centre. The treatment...

Comparison of visual field indices between normal adults and children

The authors present a prospective observational study which aimed to compare visual field indices with retinal nerve fibre layer (RNFL) thickness using optical coherence tomography (OCT) in normal adults and children. Children aged 6–18 years were recruited from a single...

My top five: Trinkets of fact or fiction

Trinkets of adult wisdom are often delivered to children alongside warnings of catastrophic outcomes. In this article we present five ‘facts’ about eye health and vision and ask the question: to what extent are these ideas backed up by literature?...

Development of a modern surgical simulation suite to promote safer ophthalmic surgical training

For trainees, having access to surgical simulation equipment is more important than ever. The authors describe the creation of a bespoke teaching and training suite in Glasgow to help trainees develop their skills and promote surgical excellence. Simulation has become...

A life outside ophthalmology

Lloyd Paul Aiello. It was an absolute privilege to speak to Lloyd Paul Aiello, Professor of Ophthalmology, Harvard Medical School, and Vice President of Ophthalmology and Director, Beetham Eye Institute, Joslin Diabetes Center, USA. Prof Aiello is a third-generation ophthalmologist,...

A review of chromosome 9p21 POAG susceptibility locus

Primary open angle glaucoma (POAG) is a genetically complex disease and the overall phenotype is influenced by multiple traits including intraocular pressure (IOP), central corneal thickness and structural features of the optic nerve head. Therefore, genes affecting any of these...