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758 results found

Risk of pulled-in-two syndrome

Congenital fibrosis of the extraocular muscles (CFEOM) is along the risk factors for pulled-in-two syndrome (PITS). The aim of this study was to report six cases and discuss prevention and clinical management strategies. The author’s six cases represented an incidence...

Childhood canalicular lacerations

This retrospective study over 10 years provides data on canalicular lacerations in patients younger than 18 years of age. Of 137 lacerations, 38 (27.7%) met the inclusion criteria. 68.4% were white and 73.7% were male. The mean age was 10.8...

Children’s clinic perceptions

The authors designed a questionnaire intended to be child friendly and for use in a paediatric ophthalmology clinic. The aim of the study was to sample the opinions of the children attending their clinics. Topics in the questionnaire included timing...

Three muscle surgery results for ET

There is limited information in the literature on the outcomes of three muscle surgery. The authors aimed to evaluate the medium term motor outcomes of three horizontal muscle surgery in 18 patients with large angle infantile esotropia of at least...

William’s syndrome

William’s syndrome is a congenital multisystem disorder involving the cardiovascular, connective tissue and central nervous systems. The aim of this study was to evaluate the frequency and severity of ophthalmic manifestations and associated diseases as well as provide epidemiology data...

A mouse model for uveal melanoma

Uveal melanoma (UM) is the most common malignant tumour arising within the eye and is a severe threat for both sight and life, due to a high risk of metastasis. There are no animal models of UM, but the Tg(Grm1)...

RPE use similar pathway to regulatory T cells to inhibit immune response

Retinal pigment epithelial (RPE) cells form an important part of the blood-retinal barrier that protects the neuronal cells responsible for sight. RPE cells are involved in innate and adaptive immune responses via expression of surface molecules and release of cytokines....

Effect of voriconazole of vision of healthy volunteers

Voriconazole is a broad spectrum, triazole antifungal agent used for systemic fungal infections. It has a favourable safety profile and is available in both intravenous and oral forms. The commonest adverse drug reactions with voriconazole are changes in visual perception,...

Canaloplasty after failed trabeculectomy

The authors describe the technique of canaloplasty performed in five patients who had undergone previous trabeculectomy and under maximum tolerated medical therapy or insufficient intraocular pressure (IOP) control. Canaloplasty is described by the authors as “a nonperforating blebless technique derived...

Comparison of five IOL formula for paediatric eyes

There is no consensus on the most suitable intraocular lens formulas for paediatric eyes to provide consistent postoperative results. This study compared modern IOL formulas to identify the smallest mean prediction error among them: Hill-RBF 2.0, Barrett Universal II (BUII),...

Impact of medical vs. surgical treatment on quality of life in glaucoma patients

The author recruited 225 patients across two sites and divided them into three groups. Group 1 medical treatment only, Group 2 surgical treatment only, Group 3 mixed medical and surgical (patients still on drops after surgery). They then used a...

Contrast sensitivity comparisons for Pelli Robson, Hiding Heidi and Double Happy tests

The authors aimed to compare contrast thresholds and measure agreement across current paediatric assessment of contrast sensitivity with Hiding Heidi and Double Happy contrast sensitivity tests vs. the gold-standard Pelli Robson chart. Reduced contrast levels were similar under different light...