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4138 results found

EEG changes following use of cyclopentolate 1% eye drops

Cycloplegic eye drops may affect the central nervous system. This study reports electroencephalogram (EEG) changes in a cohort of 6–15-year-old children. EEG recordings were taken after placebo and two doses of cyclopentolate 1% in 24 awake children (36 children had...

Progression of macular atrophy in Stargardt disease

The authors present a study of a cohort of patients with genetically proven ABCA4 gene mutation related Stargardt disease. They aimed to quantify the effect of lesion location and topography on disease progression using fundus autofluorescence imaging. One hundred and...

Ranibizumab for the treatment of age-related macular degeneration

This multicentre randomised prospective open label study compared 0.5 versus 2mg of ranibizumab in patients with submacular retinal pigment epithelial (RPE) detachment due to age-related macular degeneration. Four treatment regimens were used for the two strengths either monthly for 12...

Intermittent manual compression for CCF

Carotid cavernous fistulae (CCF) can be classified as high and low-flow or as having direct and indirect communication. Most commonly, management of high-flow CCF is with endovascular embolisation. The authors look at an alternative treatment for CCF in indirect low-flow...

Potential gender and degree of deviation bias regarding perceived urgency for surgery

This study aimed to define potential factors that influence the perceived urgency of strabismus surgery by ophthalmologists. This was a survey study which comprised questions regarding demographics of the ophthalmology respondents and a ranking of eight photos of adults with...

Comparison of five IOL formula for paediatric eyes

There is no consensus on the most suitable intraocular lens formulas for paediatric eyes to provide consistent postoperative results. This study compared modern IOL formulas to identify the smallest mean prediction error among them: Hill-RBF 2.0, Barrett Universal II (BUII),...

Parental feedback on their needs from eye services for children with congenital cataracts

The aim of this study was to analyse non-directed parental feedback to health care providers responsible for paediatric cataract care in Sweden. This was a cross-sectional study including open-ended questions. Ninety percent were mothers, and most from Sweden (82.5%) with...

Features, treatment and prevention of conjunctival inclusion cysts

Conjunctival inclusion cyst is a rare complication of strabismus surgery and generally develops at the point of muscle reattachment, caused by implantation of conjunctival epithelium. The authors aimed to determine the rate of its development after strabismus surgery and consider...

Persistent subretinal fluid (PSFF) in pneumatic retinopexy (PNR) versus pars plana vitrectomy (PPV) for rhegmatogenous retinal detachment (RRD): posthoc analysis of the PIVOT randomised trial

This is a posthoc study of the PIVOT randomised trial over a 12 month period, to evaluate the functional outcomes of the incidence of PSF in PnR versus PPV following RRD surgery. One hundred and fifty-eight patients were recruited and...

Autophagy in lens mitochondria loss

The lens consists of a monolayer of epithelial cells that overlies fibre cells that differentiate from epithelial cells at the equator. While developing, fibre cells need mitochondria to provide energy, as they mature they lose these and other organelles to...

Testing near or distance visual acuity for change during amblyopia therapy

In this study, the authors aimed to determine if any differences occurred between near and distance visual acuity (VA) in a cohort of childhood untreated amblyopia. They recruited 54 patients with mean age 4.9 years, SD 0.44. Mean VA in...

New grading description for ROP retinal changes for those meeting termination of vision screening guidelines

This study reports and characterises residual retinal changes seen in eyes that meet criteria for termination of acute retinal screening exams. A novel grading system was used in which retinal exams were graded A to E. ‘A’ was defined as...