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Corneal crosslinking in pellucid marginal degeneration

Fourteen studies were included in this first review examining the use of corneal-crosslinking (CXL) to treat pellucid marginal degeneration (PMD). PMD is a bilateral, non-inflammatory corneal thinning disorder characterised by inferior peripheral corneal thinning 1-3mm from the limbus in the...

Inverted papilloma

This is a retrospective review of 22 patients with inverted papilloma, including nine cases confined to the nasolacrimal system and 13 involving into the orbit. This is a rare disease and the report is the largest published series of periocular...

Efficacy and safety of novel PF brimonidine / timolol fixed-combination ophthalmic solution for OAG

This study is a multicentre, randomised, open-label, parallel-group clinical trial to evaluate the efficacy and safety of a newly developed preservative-free (PF) brimonidine / timolol fixed-combination (BTFC) ophthalmic solutions as compared with preservative-containing (PC) BTFC ophthalmic solution in adult patients...

Effects of ML4 on the eye

Mucolipidosis type IV (ML4) is an autosomal recessive lysosomal storage disease and is caused by variants of the MC0LN1 gene. It often presents in young individuals with eye and ocular adnexa issues. The authors present a case report and literature...

Monofixation syndrome following cataract extraction

This study aimed to test the hypothesis that interruption of macular fusion for an extended period of time is the key event that results in the development of monofixation syndrome in children and adults. This was a retrospective review of...

Treatment of infantile cataract with secondary IOLs

The authors examined whether secondary IOL insertion is helpful in the successful treatment of monocular infantile cataracts. Eleven children were reviewed: eight with cataract extraction at one to four months of age and three at five to seven months of...

Surgical outcomes after trauma-induced cataract extraction

This study evaluated outcomes in children aged less than eight years with corneal laceration and traumatic cataract who had cataract extraction one to eight weeks after primary corneal wound repair. This was a retrospective study of 47 eyes of 47...

Congenital aniridia with or without retinal detachment

The authors present the clinical and molecular genetic evaluations performed on a large Iranian pedigree with 26 aniridia affected patients in four generations and some with retinal detachment. Members of the family affected with aniridia were invited to participate after...

Patients prefer vision from lasik than from smile in a contralateral-eye trial

This prospective, randomised, single surgeon, contralateral-eye clinical trial compared the results in myopic patients undergoing wavefront-guided femtosecond laser in situ keratomileusis (LASIK) in one eye and small-incision lenticule extraction (SMILE) in the fellow eye. The patient-reported outcomes with laser in...

Long-term meibomian gland function following a single thermal pulsation treatment

Dry eyes secondary to blepharitis and or meibomian gland dysfunction, though extremely common, is an annoyingly difficult condition to treat for several patients. Part of this difficulty lies in the inability of most patients to follow intensive and often times...