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Silicone hydrogel contact lenses versus autologous serum drops for dry eyes in Sjörgen syndrome
A total of 37 patients with Sjörgen syndrome (SS) related dry eyes reporting symptoms on standard therapy with artificial tears and anti-inflammatory drops were evaluated in this trial. They were randomly assigned to additional treatment with either balafilcon A silicone...
Non-contact-lens-associated acanthamoeba keratitis
This retrospective study was done to study the clinical presentation and microbiological results of non-contact-lens-related acanthamoeba keratitis (AK). One hundred and ninety-four patients with microbiological / histopathological diagnosis of AK over four years were included. All patients had corneal scrapings...
Relationship between nocturnal intraocular pressure elevation and diurnal intraocular pressure level in NTG patients
This group studies Korean normo-tension glaucoma (NTG) patients over a 24-hour period to assess if there was a relationship between nocturnal intraocular pressure (IOP) and diurnal IOP. They have previously suggested differences in diurnal IOP may have varying mechanisms of...
Effect of change in retinal nerve fibre layer thickness on quality of life in patients with glaucoma
The authors investigated the relationship between structural changes in glaucoma (retinal nerve fibre layer (RNFL) thickness) and quality of life (as measured by the NEI VFQ-25 questionnaire) over a period of time. Two hundred and sixty eyes of 130 patients...
Biodegradable plates in lateral orbitotomy surgery
This is a description of a new method for fixating the bone flap during a lateral orbitotomy. The technique involves the use of an absorbable lactide plate. This is warmed in a water bath to allow trimming and moulding to...
Expert vs. non expert grading of ROP from digital video images
The primary purpose of this study was to determine whether digital video images of the retina obtained using an indirect ophthalmoscope imaging system could be accurately graded for zone and stage of retinopathy of prematurity (ROP) and the presence of...
Smartphone based visual acuity
Smartphone technology is becoming widely available to all age groups and settings. Apps using Snellen acuity charts are widely available and this study evaluated the equivalence of a smartphone-based visual acuity chart with a standard 6m Snellen visual acuity (6SVA)...
Exposure to atomic bomb radiation and age-related macular degeneration in later life
This paper is one of the outcomes of the Adult Health Study; a cohort study of the atomic bomb survivors of Hiroshima-Nagasaki in Japan. It investigates the proposed association between pasty radiation exposure early in life and the presence of...
Analysis of risk factors for intraocular pressure rise following insertion of fluocinolone acetonide injection in uveitic patients
For this study, the authors analysed the pooled data from three phase2b / 3 multi-centre randomised controlled trials carried out over three years. Included patients had undergone at least one of the following treatments: 1) systemic therapy (corticosteroid / immunosuppressant...
Intensive diabetes therapy and ocular surgery in type 1 diabetes
The Diabetes Control and Complications Trial (DCCT) ran between 1983 and 1993 and showed that intensive glycaemic control was beneficial in reducing diabetic retinopathy in type 1 patients. There was a 76% reduction in onset of retinopathy and a 52%...
Long-term effect of gene therapy on Leber’s congenital amaurosis
After reporting the first successful gene therapy results for RPE65 deficiency in three patients in a brief report in 2008, the same team from London now report the results of 12 patients followed up for three years after transfection. As...
