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637 results found

Bilateral internuclear ophthalmoplegia

Bilateral internuclear ophthalmoplegia (INO) has been linked with various pathological conditions of the central nervous system such as multiple sclerosis, stroke, tumours and brainstem inflammatory processes. This unusual case report describes a case of a 45-year-old female patient presenting with...

Visual snow syndrome: a review

Visual snow syndrome (VSS) is a neurological condition characterised by visual phenomena described as dots moving across the visual field. Other visual symptoms can take the form of palinopsia, entopic phenomena, photophobia and nyctalopia. Tinnitus and migraine can be commonly...

Syndromic V-pattern management

The authors document their experience in the management of four cases of Crouzon syndrome and review the anatomical extraocular muscle anomalies noted during surgery. Horizontal strabismus surgery varied in each of the four cases according to individual extraocular muscle abnormalities...

The expanding spectrum of idiopathic intracranial hypertension

This is a review article from a tertiary centre in Atlanta, US. With rising obesity rates and increasing access for MRI scans there has been a large increase in patients requiring an urgent papilloedema check with incidental findings on MRI...

Systemic rituximab immunotherapy in the management of primary ocular adnexal lymphoma single institutional experience

Ocular adnexal lymphomas constitute 2% of all non-Hodgkin’s disease and 5-15% of all extranodal lymphomas and are usually localised, low-grade and of B-cell origin. This opens them up to potential treatment with a systemic monoclonal antibody-based drug (rituximab) directed at...

Brn3b neuroprotective effect in rat glaucoma model

An adeno-associated virus-directed overexpression of the Brn3b protein in hypothesised to confer neuroprotective effects in this paper. This is ultimately tested in a well-accepted rat glaucoma model (Morrison’s model: saline injection into episcleral veins of rat eyes with a force...

Rare case reports of benign optic glioma in adults with clinically aggressive nature

Primary optic nerve gliomas are most commonly benign and occurring in childhood. Malignant optic gliomas occur in adulthood and follow an aggressive course usually leading to blindness and death within months. This paper describes the clinical and histopathological features of...

Childhood canalicular lacerations

This retrospective study over 10 years provides data on canalicular lacerations in patients younger than 18 years of age. Of 137 lacerations, 38 (27.7%) met the inclusion criteria. 68.4% were white and 73.7% were male. The mean age was 10.8...

Adolescent optic disc haemorrhages

The authors conducted this study to describe the clinical characteristics of multi-layered optic disc haemorrhages in adolescents. This was a retrospective review of 16 eyes (11 right and five left) of 16 patients with a mean age of 15 ±2.6...

Two case reports of late onset adbucens nerve palsy following carotid-cavernous fistula treatment

This report presents two cases of abducens palsy developing with late onset following endovascular treatment for carotid-cavernous fistula. Following this common and effective treatment for carotid-cavernous fistula, an immediate cranial nerve palsy is a common finding. It usually resolves spontaneously....

Features and outcomes of pulled-in-two syndrome

Pulled-in-two (PIT) syndrome is a sudden rupture of the extraocular muscle during strabismus surgery, typically with minimal tension intraoperatively without excessive force. This is a rare occurrence and this study reports cases from a single centre over a seven-year period....

Case reports of neuro-ophthalmological complications of CIPD

The authors present three cases of neuro-ophthalmological complications of chronic inflammatory demyelinating polyradiculoneuropathy (CIPD). CIPD can lead to prominent nerve hypertrophy which can mimic other forms of neuropathy radiologically. In addition, complications can occur which can cause diagnostic difficulties. All...