You searched for "inflammation"
Effect of topical diclofenac on postoperative PRK pain: RCT
A major disadvantage of excimer laser photorefractive keratectomy (PRK) is pain and discomfort after the surgery, which is thought to be due to damage to corneal sensory nerve fibres or local release of inflammatory substances. Pain only resolves once corneal...
Inhibiting high-risk corneal allografts
The cornea is an immune privileged site and as such corneal transplants are very successful. However, in situations where this privilege is lost the failure rises substantially. To combat rejection inhibition of the immune responses depends on steroids and other...
Injection of methotrexate into silicone oil-filled eyes for grade C PVR
Methotrexate (MTX) is an antineoplastic antimetabolite with immunosuppressant properties. Folate antagonism is known to contribute to the antiproliferative effects of MTX, and release of adenosine from cells and inhibition of polyamines may explain its anti-inflammatory effects. These activities contribute to...
Pain control during orbital implant surgery
This is a study based on existing evidence that pre-emptive pain control has advantages over traditional post-surgical analgesia. The authors compared pain scores in three groups of randomly assigned and masked patients all undergoing orbital implant surgery under general anaesthesia...
Corneal lenticule allotransplant
This animal study looked at corneal lenticule allograft transplantation in rabbits. Seven rabbits underwent small incision lenticule extraction (SMILE) procedures, where their stromal lenticules were extracted and transplanted fresh into pre-prepared corneal stromal pockets of seven recipient eyes. Animals were...Herpes zoster ophthalmicus: a clinician’s perspective
Introduction Herpes zoster, commonly known as shingles, is caused by the reactivation of varicella zoster virus (VZV). The term herpes is derived from a Greek work, herpein, which means ‘creeping’ and the word zoster means a belt or a girdle...
Effects of ML4 on the eye
Mucolipidosis type IV (ML4) is an autosomal recessive lysosomal storage disease and is caused by variants of the MC0LN1 gene. It often presents in young individuals with eye and ocular adnexa issues. The authors present a case report and literature...Fusarium keratitis in a patient with alcohol dependence
Treatment of fungal keratitis secondary to the Fusarium species remains a challenge. Although relatively more common in warmer climates, this corneal infection is rare in the UK. Most cases have been reported in farmers and are often preceded by trauma....Non-arteritic anterior ischaemic optic neuropathy (NA-AION): a review
Ischaemic optic neuropathy (ION) is the commonest adult optic neuropathy encountered today in our ageing population, is a common cause of irreversible visual loss and is usually associated with underlying vascular disease. The condition is classified as follows: (a) Anterior...Typical or surprisingly uncharacteristic presentations of neuro-ophthalmic emergencies
Irrespective of geographical location or patient cohort, emergency departments are high risk locations capable of inspiring extreme anxiety and dread in patients and doctors alike. The stress multiplies when a walk-in or referred case is suspected of underlying neurological pathology....RCOphth (The Royal College of Ophthalmologists) Cataract Surgery Complications
This course will focus on the practical management of posterior capsule rupture and zonular dialysis. This will be a “hands on” course with the emphasis on practicing anterior vitrectomy techniques, the use of capsular tension rings, capsule hooks and sulcus IOL implantation. There will also be interactive small group teaching on how to prevent surgical complications during phacoemulsification surgery. The course is aimed at ST5-ST7 trainees, Fellows and Consultants.
