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Leber’s hereditary optic neuropathy: from lab to clinic

1 October 2016 | | EYE - Neuro-ophthalmology | Hereditary optic neuropathy, Leber hereditary optic neuropathy, mitochondrial optic neuropathy, optic neuropathy
Leber’s hereditary optic neuropathy (LHON) was the first clinically described mitochondrial disorder (1871). This article reviews the pathophysiology and clinical features of LHON with a focus on translational research. G11778A is currently the most common mutation worldwide and is associated...

Exciting opportunities for ophthalmic surgeons with the UK and Europe’s leading private provider of cataract surgery, lens replacement surgery and laser eye surgery

17 July 2023 | Recruitment & Personnel
At Optical Express we are focused on delivering exceptional patient care, outstanding clinical outcomes and continued investment in our people and technology. For over 30 years, millions of patients have trusted Optical Express with their eye care.

The role of aspirin in the treatment of NAION: Benefits and controversies

4 December 2024 | | EYE - Neuro-ophthalmology
Non-arteritic anterior ischaemic optic neuropathy (NAION) is the most common acute optic neuropathy in individuals over 50 with estimated prevalence of 2–10 per 100,000 people, characterised by sudden, unilateral vision loss due to ischaemic injury to the optic nerve head....

COVID-19: Pete’s Bogus Journey

6 April 2021 | | EYE - General
The author shares his personal experience of contracting coronavirus. I managed to body swerve COVID-19 for nine months. The Pfizer vaccine was being rolled out in my trust. I had my first inoculation booked in three weeks. I had survived...

People watching…

5 June 2023 |
Confession time: I love a good airport lounge! Not only does it mean that you are about to go get some sunshine on a well-deserved break, it also provides a perfect opportunity to watch people go by. And what a...

Interspecialty referrals

4 February 2021 | | EYE - Cataract, EYE - Cornea, EYE - Glaucoma, EYE - Imaging, EYE - Neuro-ophthalmology, EYE - Oculoplastic, EYE - Oncology, EYE - Orbit, EYE - Paediatrics, EYE - Pathology, EYE - Strabismus, EYE - Refractive, EYE - Vitreo-Retinal, EYE - General
Referrals between the many and varied branches of ophthalmology sometimes underline how sub-specialised we have all become nowadays. The old era when everyone was an ophthalmic jack of all trades is gone, for better or for worse, and instead of...

How to nearly (but not quite) get into ST1 ophthalmology training – some reflections

1 February 2022 | | EYE - General
Ophthalmology is often considered to be an elite, highly competitive specialty, with little room for failure. Candidates and trainees tend to cultivate a certain urbane and confident style, and the bottleneck at ST1 can feel rather intense. The majority of...

What's trending Dec/Jan 2022

1 December 2021 | | EYE - Imaging, EYE - Vitreo-Retinal, EYE - General
A round-up of the eye-related hot topics that have been trending on social media over the last few weeks. #eyetrackingtechnology #assitivetechnology #gaming Modern eye trackers often rely on electronic specialist hardware that continuously scan the the pupil and reflections from...

What’s Eating Gilbert Pete

2 August 2022 | | EYE - General
“Please phone Mr C Lyon ASAP on 0131 334 9171” This was a message from my secretary waiting for me on my computer one morning shortly after I was appointed a consultant. The name did not ring any bells but...

Coaching: Supporting doctors’ development and wellbeing

20 October 2025 | | EYE - General
Supporting and retaining the workforce is a top priority for all NHS organisations, but it’s not clear how best to do this, or how such support should be funded. Junior doctors have clinical and educational supervision, and the quality of...

Low vision support in teenagers

4 December 2025 | | EYE - Paediatrics
As society places increasing emphasis on mental health and access to technology increases, the structure and prioritisation within low vision appointments is evolving. These changes bring new challenges and demands in terms of our clinical support, requiring us to consider...

Communication in ophthalmological surgery: Perspectives from an observer

3 February 2026 | | EYE - Cataract
"Please don’t move” is a common phrase I have heard whilst shadowing in theatres as the ophthalmologist contends with the eye of a patient looking around and tilting their head during surgery. As the average corneal diameter is approximately 12–12.5mm...