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2031 results found

Corporate M&A pace gathers momentum

Intensifying franchise competition, maturing product development pipelines and looming loss of exclusivity spur renewed merger and acquisition (M&A) activity in the ophthalmics sector. Rod McNeil reviews recent deals and related strategic developments. AbbVie to acquire Allergan in $63 billion mega-combination,...

OCT Angiography in Retinal and Macular Diseases

OCT angiography (OCT-A) is based on the concept that in a static eye, the only moving structure in the fundus of the eye is blood flowing through the vessels. This book explains how the technique allows a depth-resolved analysis and...

Embedding EMR for a complete transformation in user experience

Informatics and IT projects in the NHS have a history of being over budget, delivered late and not fulfilling the design brief. “But it doesn’t have to be that way,” believes Chris Canning, Consultant Ophthalmologist and Chief Clinical Information Officer...

Changes in corneal endothelial layer after strabismus surgery

The purpose of this study was to investigate the changes in the corneal endothelial layer by specular microscopy after surgery in patients with horizontal and oblique strabismus. Eighty-three eyes of 56 patients were evaluated prospectively. There were three subgroups: one...

A clinical review of optic neuropathy associated with amiodarone

The authors present a clinical overview of the occurrence of visual loss secondary to optic neuropathy associated with the use of the antiarrhythmic agent amiodarone. Amiodarone is prescribed for the management of atrial fibrillation and ventricular tachycardia / fibrillation. However,...

New grading description for ROP retinal changes for those meeting termination of vision screening guidelines

This study reports and characterises residual retinal changes seen in eyes that meet criteria for termination of acute retinal screening exams. A novel grading system was used in which retinal exams were graded A to E. ‘A’ was defined as...

The COVID-19 ‘frontlines’: a foundation doctor’s perspective

Staring through the fragmented stained glass of the Virgin Mary and her assorted angels, I reflected on the strangeness of the workplace I now found myself working in and the irony of a workforce now working together more enthusiastically than...

Intravitreal Ziv-Aflibercept: safety analysis

Ziv-Aflibercept (Zaltrap; Sanofi-Aventis U.S LLS, Bridgewater, NJ) was originally introduced as an intravenous formulation for metastatic colorectal cancer. The adoption of Ziv-Aflibercept in ophthalmic practice was similar to bevacizumab, and reports have previously examined one to two year visual outcomes...

Pharmacopoeia of the Royal Infirmary of Edinburgh

The compact volume depicted in Figure 1 bears the simple title Pharmacopoeia. The book originally belonged to the author’s father, the late John King. A pharmacist by profession, John King maintained a keen interest in matters pertaining to pharmaceutical history....

The bionic eye – behind the headlines

Multiple visual prosthetic projects and other vision regeneration initiatives being tested in preclinical and clinical development worldwide illustrate continuing progress and opportunities in addressing profound blindness from hereditary retinal diseases and other causes (Table 1). Three implantable bionic vision systems...

Guideline considerations for management of paediatric traumatic cataract

This study aimed to develop guidelines for preoperative decision-making and perioperative management of paediatric traumatic cataract patients. A 24-question survey was designed to assess surgeon background, preoperative planning and testing, surgical timing, intraoperative techniques and postoperative management. Anonymous responses were...

Learning from litigation: ocular drug toxicity

Being the subject of litigation is stressful and upsetting. Having to look back over your previous decisions and justify the care you delivered in good faith can be difficult. Sadly, we all live with the sword of Damocles above us...