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Familial Mediterranean Fever and keratoconus
This retrospective case control study was conducted in the Genetic Diagnostic Centre in Turkey. It examined the prevalence of keratoconus in two groups; patients with Familial Mediterranean Fever (FMF) and age matched controls free of FMF, who were tested for...
Myopia in Han Chinese
The authors present a case-control study of 361 patients with high myopia (mean spherical equivalent of -6.0DS or lower, and axial length greater than or equal to 26mm) and 749 healthy controls (mean spherical equivalent -1.0 to +1.0DS). They tested...
Comparison of central laminar thickness in optic neuropathy and normal eyes
The study compares central laminar thickness (LT) among patients with glaucomatous optic neuropathy (GON), patients with non-GON and normal subjects. The non-GON group comprised eyes with demyelinating optic neuropathy (ON), anterior ischaemic ON, compressive ON, Leber hereditary ON and traumatic...
RCT of IOL type
The optical performance of pseudophakic eyes were compared after implantation of spherical and aspheric IOLs in paediatric patients after cataract surgery. This randomised controlled trial included 40 eyes of 23 patients: 20 eyes in each group. Follow-up was over three...
Differential inhibition of EAU by CTLA4 and IL-6
Cytotoxic T lymphocyte antigen-4 (CTLA4) binds both CD80 and Cd86 and inhibits T lymphocyte activation via CD28. Il-6 is a pleiotropic cytokine that has been associated with many autoimmune conditions including uveitis. Blockade of these molecules by either CTLA4-Ig, a...
Normal videonystagmography data
The authors report on the smooth pursuit and saccadic eye movement waveforms elicited from normal patients while viewing standardised calibrated targets. Serial trials were performed on each patient to determine test / retest reliability: nine trials producing 117 results by...
AMD and visceral fat and pro-inflammatory factors
Several large studies have shown a positive relationship between age-related macular degeneration (ARMD) and high body mass index. The waist-hip ratio is also associated with development of early AMD. Visceral fat has a pro-inflammatory effect, which means it has an...
The impact of collagen crosslinking on keratoplasty numbers in keratoconics
A question of corneal cross-linking (CXL) reducing keratoplasty numbers in keratoconics was addressed in this single centre observational study from the Oslo University Hospital – a sole provider of keratoplasties and CXL for a population of 2.8 million. Authors compared...
Rituximab as an immunosuppression treatment for thyroid eye disease
Thyroid eye disease is traditionally treated with high dose glucocorticosteroids and surgical orbital decompression, where responses are often inadequate. This medical treatment is centred around symptom control and reduction of thyroid hormone synthesis, not immunosuppression. Rituximab is an anti-CD20 monoclonal...
Smoking and Behçet’s disease
This study aimed to investigate the relationship between smoking and prognosis of ocular Behçet’s disease (BD). Records of 202 patients with ocular features of BD were reviewed from a Turkish hospital. Patients were divided into two groups according to their...
The impact of conjunctivochalasis on dry eye symptoms and signs
The study aimed to draw a relationship between conjunctivochalasis and dry eye symptoms via a dry eye questionnaire (DEQ5), as well as signs such as tear osmolarity, tear break up time, corneal staining, Schirmer score, meibomian gland dropout, eye lid...
