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Distribution, progression, and outcomes of inflammatory chorioretinal lesions

This study investigated the distribution and progression of multifocal choroiditis (MFC) inflammatory lesions in 25 eyes of 20 patients and their correlations with clinical outcomes at 24 months. The distribution of choroiditis inflammatory lesions were evaluated semi-automatically using a dedicated...

Comparison between findings in ‘active’ or ‘healed’ giant cell arteritis

Giant cell arteritis (GCA) is the most common systemic vasculitis in older people and can cause devastating sight loss if untreated. Temporal artery biopsy is often relied upon for diagnosis by ophthalmologists, with a positive biopsy result indicating whether the...

Delayed EPBRT efficacy in retinoblastoma

This is a retrospective medical records review of 50 patients (54 eyes) with retinoblastoma (RB), who received I-125 episcleral plaque brachytherapy (EPBRT) prior to (primary) or following chemoreduction (delayed) alone and in combination with non-irradiative focal therapy. Fifty-six plaques were...

Blindness from some inherited eye diseases may be caused by gut bacteria

Sight loss in certain inherited eye diseases may be caused by gut bacteria, and is potentially treatable by antimicrobials, finds a new study in mice co-led by a UCL and Moorfields researcher.

“Steel True, Blade Straight”

Steven Kerr of the Royal College of Surgeons of Edinburgh explores the medical career of Arthur Conan Doyle, his relationship with his mentor Joseph Bell and his fascination with ophthalmology. Arthur Ignatius Conan Doyle was born in Edinburgh on the...

Characteristics and incidence of sixth nerve palsy in children with intracranial hypertension

The authors report the incidence and characteristics of sixth cranial nerve palsy in paediatric patients with intracranial hypertension. A retrospective review of records was performed in central Ohio over a three year period and nine children were found to have...

A career in uveitis

As he retires from clinical practice, the author looks back on his long career in uveitis and how care of these patients has changed dramatically since his days as an undergraduate. My trainees and fellows are often bored by my...

Closed-chamber haptic re-externalisation for posteriorly displaced sclerotomy and inadequate haptic tuck in glued posterior chamber intraocular lenses

This technique (online video http://jcrsjournal.org) emphasises the importance of both symmetrical and sufficient anterior placement of sclerotomies to externalise an adequate length of the haptics, which in turn provides good centration and stability of the intra-ocular lens (IOL). The authors...

It’s not all about ARED - Time for a pragmatic approach to nutrition for eye health?

Advances in treatment for retinal diseases involving neovascularisation have undoubtedly changed the future of eye care across the UK for the better, but also created great challenges for service delivery in ophthalmology, particularly within the NHS. Some statistics are starting...

Surgeons can lead the way in transforming global health

Surgeons must provide leadership in transforming healthcare across the Global South – by integrating surgery into the global health agenda and advocating for simple and cost-effective surgical procedures that support overall health system strengthening.

Part 1: good news, bad news at the international conference

One of my favourite comic strips from my childhood was Good News, Bad News which ran in Jackpot comic from 1979–1982. In this strip, the story for the main character would be described in a series of alternating ‘Good News’...

Embryology in clinical practice

The fascinating world of embryology is both beautiful and practical. It is a home video of our evolutionary history through the ages from the single cell through to the life aquatic, the development of gut, limbs and brain, and most...