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Renewed momentum in ocular gene and cell therapy, broadening application to chronic disease

Gene and cell therapies offer the prospect of ground-breaking new avenues for the treatment of diseases, reflected in a renewed explosion of interest and investment in retinal gene therapy. Rod McNeil reports recent clinical trial readouts across a diverse range...

25-gauge PPV for retained lens fragments

This was a retrospective study including 40 eyes of 40 patients with mean age of 78 years, 19 females and 21 males, who underwent 25-gauge pars plana vitrectomy (PPV) for retained lens fragments with a minimum of six months of...

We are all Hadiza

When I worked as a registrar at Newport many years ago I remember a no-nonsense corneal consultant railing about the way the tragic case of Lucie Linforth was being reported in the media. Lucie was a toddler taken into a...

Doing a systematic review: a users’ guide for foundation doctors

Research is increasingly important for junior doctors and systematic reviews (SRs) are a great place to start. Carrying out an SR can help a doctor demonstrate commitment to a specialty, develop research skills and get results quickly. This article aims...

Fight for Sight to maximise impact by funding solutions-focused research in priority eye conditions

Fight for Sight aims to stop sight loss by funding pioneering research. Rod McNeil takes a look at the Primer Fellowship Awards programme, which provides funding for up to £60,000 for individuals to undertake vision-related research for one year. Among...

Insects, swelling and sight loss: a case of orbital inflammatory syndrome

Despite being the most common cause of painful orbital mass in adults and the third most common orbital disease, orbital inflammatory syndrome still proves to be a difficult ocular condition to diagnose, treat, and manage. A 41-year-old lady presented to...

An update on inherited retinal disorders (part 2): Approaches to therapy for IRDs

Part 1 of this topic can be found here There are currently no proven cures for inherited retinal disease (IRD). However, multiple avenues of research are being investigated to better understand disease mechanisms and trial potential therapies that may slow...

An update on inherited retinal disorders (part 1) – overview and assessment of inherited retinal disease

Part 2 of this topic can be found here Inherited Retinal Disease (IRD) is the leading cause of blindness certification in the working age population (age 16-64 years) in England and Wales and the second most common in childhood [1]....

The International Congress of Ophthalmology (ICO): a history

Readers of Eye News will notice in the Events section that the World Congress of Ophthalmology (WOC) is scheduled to take place in Barcelona in June 2018. This is in fact the renamed International Congress of Ophthalmology (ICO) and now...

Birdshot retinochoroiditis

Birdshot retinochoroiditis (BRC) is a chronic, sight-threatening uveitis, most commonly affecting caucasian individuals in their fourth to sixth decades [1]. The disease is associated with HLA-29 and is characterised by progressive inflammation at the level of retina and choroid, with...

What’s Eating Gilbert Pete

“Please phone Mr C Lyon ASAP on 0131 334 9171” This was a message from my secretary waiting for me on my computer one morning shortly after I was appointed a consultant. The name did not ring any bells but...

Why Ophthalmology?

Ophthalmology is a medical specialty that deals with eye diseases and helps preserve vision. The ophthalmic community consists of a wide range of healthcare professionals who work together to address eye-related problems in many extraordinary ways. This article explores the...