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Risk factors for NTG in a young Korean population

Previously known ocular and systemic risk factors for normal tension glaucoma (NTG) include myopia, peripapillary atrophy, disc haemorrhage, migraine, obstructive sleep apnoea, thyroid disease and cerebral infarction. However, most NTG risk factor studies have examined patients aged 40 years and...

Conjunctival inflammation in glaucoma patients

Numerous studies have demonstrated that topical medications and preservatives used for the management of glaucoma can induce significant histopathologic and inflammatory changes in the ocular surface. This study describes an increased expression of major histocompatibility complex class II antigen HLA-DR,...

Eye drop prescription and usage in glaucoma patients

The authors describe a study using a questionnaire to determine how patients use their glaucoma medications to investigate the association between patterns of eye drop prescriptions and medication use. They enrolled 67 Japanese patients who had been prescribed topical anti-glaucoma...

Reproducible OCT RNFL map in unilateral glaucoma

The aim of the study was to compare the reproducibility of the optical coherence tomography retinal nerve fibre layer (OCT RNFL) thickness map between glaucomatous and fellow normal eyes of unilateral glaucoma patients. The authors carried out a prospective case...

Long scleral tunnel technique to prevent tube exposure of Ahmed glaucoma valve

This retrospective study was done to evaluate the efficacy of long scleral tunnel technique and compare it with pericardium patch graft in preventing tube exposure of Ahmed glaucoma valve. Seventy-eight eyes of 73 patients were included. In group 1 patients,...

Comparison between findings in ‘active’ or ‘healed’ giant cell arteritis

Giant cell arteritis (GCA) is the most common systemic vasculitis in older people and can cause devastating sight loss if untreated. Temporal artery biopsy is often relied upon for diagnosis by ophthalmologists, with a positive biopsy result indicating whether the...

Clinical predictors of proliferative sickle cell retinopathy

Sickle Cell Disease (SCD) is an inherited disorder resulting in production of Haemoglobin S (HbS), which aggregates in conditions of hypoxia, acidosis or hyperosmolarity. This leads to vascular stasis, thrombosis and ischaemia. The authors present a cross-sectional study (45 consecutive...

Choice of diclofenac or corticosteroids for strabismus surgery

This systematic review was undertaken to analyse the available data on various corticosteroids and diclofenac to determine the most effective postoperative anti-inflammatory agent for patients with strabismus. Twenty-five studies were identified from 1997–2021 and a total of eight met the...

Laser speckle contrast imaging (LSCI) enables perfusion monitoring of the anterior segment during strabismus surgery: a study on the horizontal rectus muscles

Forty-four eyes with horizontal strabismus surgery involving medial and / or lateral rectus muscle detachment were recruited. The perfusion in the adjacent paralimbal and iris tissue was monitored with LSCI technique, by using a PeriCam PSI NR System. An infrared...

Progression of macular atrophy in Stargardt disease

The authors present a study of a cohort of patients with genetically proven ABCA4 gene mutation related Stargardt disease. They aimed to quantify the effect of lesion location and topography on disease progression using fundus autofluorescence imaging. One hundred and...

Methotrexate and mycophenolate mofetil for non-infectious uveitis

This is the first reported randomised clinical trial comparing methotrexate versus mycophenolate mofetil (MMF) for the treatment of non-infectious intermediate uveitis, posterior uveitis or panuveitis. To be eligible for recruitment, patients had to be on ≥15mg oral prednisone and demonstrated...

Effect of oxygen levels on binocular summation of dark vision

Previous studies have reported conflicting results on the existence of binocular enhancement of dark vision. This study compares monocular and binocular absolute thresholds of dark adaptation in two different populations (healthy individuals and those with chronic respiratory insufficiency). The study...