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Management of giant retinal tears with vitrectomy and perfluorocarbon liquid postoperatively as a short-term tamponade

The authors report an eight year retrospective case series study of 30 eyes of 29 patients with who underwent a giant retinal tear-related retinal detachment repair. M: F ratio was 23:6. Right to left eye ratio was 16:14. The mean...

Stereotactic radiotherapy for polypoidal choroidal vasculopathy

Polypoidal choroidal vasculopathy (PCV) is a variant of neovascular AMD. It is a disease of choroidal vasculature characterised by abnormal branching vascular network with aneurysmal dilatations (polyps). Features of PCV include pigment epithelial detachments (PED), subretinal fluid (SRF) accumulation and...

RaScaL Study

The RaScaL study was a six month, single-centre, controlled, prospective phase I/II study in which subjects with diabetic macular oedema (DME) and associated peripheral nonperfusion on ultrawide-field fluorescein angiography (UWFA) were randomised to: (1) study arm: ranibizumab (0.5 mg) injection...

Orbital cellulitis in Scotland: current incidents, aetiology, management and outcomes

This is a one year prospective study using the Scottish ophthalmic surveillance unit reporting system amongst Scottish ophthalmologists. Only patients residing within Scotland with a new diagnosis of orbital cellulitis between November 2011 and October 2012 were including in this...

Efficacy of intravitreal dexamethasone implant in patients with persistent macular oedema

Chronic cystoid macular oedema (CME) can develop secondary to various pathologies such as diabetic maculopathy, retinal vein occlusion and uveitis. It can cause significant visual impairment and macular damage. The therapeutic effect of corticosteroids in CME is through one or...

Safe cataract extraction with underlying hypotonous cilio-choroidal detachment following trabeculectomy surgery

The authors of this study (including the reviewer of this article) describe a surgical technique for phacoemulsification in the presence of shallow choroidal detachment owing to hypotony following trabeculectomy. In their case series, four eyes of four patients with advanced...

Incidence and risk factors of ocular hypertension following PPV and SOI

In this prospective, interventional study the authors evaluated the risk factors for elevated intraocular pressure (IOP) after pars plana vitrectomy (PPV) with silicone oil injection (SOI). This study included 254 eyes of 254 patients, with a mean age of 55.33...

Endophthalmitis after intravitreal anti-VEGF injection

The authors report the results of a retrospective multicentre study conducted at 17 retina referral centres to investigate the microbial spectrum of endophthalmitis after anti-VEGF injections. A total of 83 cases of culture-positive endophthalmitis (58.4%) were included. The most frequent...

Suture-less flanged IOL fixation vs. conventional sutured SF in IOL dislocation

The authors report the analysis of a prospective, comparative cohort study on 103 consecutive patients (103 eyes) with intraocular lens (IOL) dislocation who underwent vitrectomy with IOL removal and sutured scleral fixation (SF) (53 eyes) or flanged IOL fixation (50...

Detecting apoptosis in retinal cells

This is a review paper in which the authors summarise the transitioning of techniques detecting apoptosis from bench to bedside, along with the future possibilities they encase. Detection of Apoptosis in Retinal Cells (DARC) technology can be used as a...

Effect of syringe-filling technique and risk for endophthalmitis after intravitreal injection of anti-VEGF agents

In this retrospective study the authors compare the risk for post-injection endophthalmitis between different anti-vascular endothelial growth factor (VEGF) agents and syringe preparation technique. This multicentre study included 197,402 injections. The drugs included in this study were three Anti-VEGF agents...

Post hoc analysis of the CANTREAT randomised trial

CANTREAT, a Canadian multicentre two-year randomised trial compares treat and extend treatment (T&E) relative to the monthly administration of Ranibizumab in nAMD. Two-hundred and eighty-five treatment-naïve patients with nAMD were randomised to receive either a once-monthly dosing or T&E regimen...