You searched for "VEGF"
Macular atrophy and choriocapillaris nonperfusion
1 April 2019
| Saruban Pasu
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Retina / Uvea / Vitreous
This Japanese study compared the choriocapillaris (CC) nonperfusion area as measured on OCTA with areas of macular atrophy (MA) measured by fundus autofluoresence (FAF). A total of 44 eyes were assessed (31 were treated with anti-VEGF alone and 13 had...
DRIL after macular oedema treatment in BRVO
The authors report the analysis of a single-site, retrospective, cross-sectional study to evaluate the association between disorganisation of the retinal inner layers (DRIL) and visual acuity (VA) after anti-VEGF treatment for macular oedema (MO) due to branch retinal vein occlusion...Pathophysiology of diabetic macular oedema: why combination therapy may be better
1 October 2015
| Winfried MK Amoaku
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Retina / Uvea / Vitreous
The prevalence of diabetes has continued to increase over the years. It is currently estimated that there are 382 million with diabetes worldwide in 2013, and that this figure is expected to rise to 592 million by 2035 [1]. In...
RPE atrophy onset in treated nAMD
1 October 2019
| Sofia Rokerya
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Retina / Uvea / Vitreous
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Age-related macular degeneration, Aqueous humor, Atrophy, Complement, Vascular endothelial growth factor
In this study the authors aim to evaluate the role of various factors for the development of retinal pigment epithelium (RPE) atrophy over a period of five years in patients with nAMD. Fifty-two newly diagnosed nAMD patients with complete absence...
Autofluorescence patterns in subretinal haemorrhages associated with neovascular age-related macular degeneration
2 August 2024
| Sofia Rokerya
|
Retina / Uvea / Vitreous
The aim of this retrospective study was to describe the surgical results and fundus autofluorescence (FAF) patterns occurring in sub-macular haemorrhage (SMH) of duration <60 days in age-related macular degeneration (AMD). Notes from 39 eyes of 39 patients with SMH,...
Wet AMD outcomes post cataract surgery
3 June 2021
| Kareem Waleed Alsaffarini
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Cataract and Refractive
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age-related cataract, antivascular endothelial growth factor, cataract surgery, wet age-related macular degeneration
The authors present the findings of a retrospective study looking at the progression of wet age-related macular degeneration (AMD) in patients who underwent cataract surgery. They recruited a series of 111 patients of which 38 were men and 73 were...
Comparison of treatment regimes for APROP
5 August 2022
| Fiona Rowe (Prof)
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Paediatric Ophthalmology / Strabismus
The authors evaluated the risk factors and treatment outcomes of various treatment options for APROP including intra-vitreal anti-VEGF injections, laser treatment and a combination of both. This was an observational study of all consecutive cases of untreated APROP from 2018-19...
ROP screening criteria
7 April 2021
| Fiona Rowe (Prof)
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Paediatric Ophthalmology / Strabismus
This study aimed to describe a process of identifying birth weight and gestational age screening guidelines in Mongolia using telemedicine for retinopathy of prematurity (ROP) screening. This was a single centre prospective study collecting data from December 2016 to January...
Do bilateral same day intravitreal injections increase the risk of endophthalmitis?
1 February 2019
| Tasmin Berman
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Retina / Uvea / Vitreous
This large retrospective cohort study reviewed all patients who had bilateral intravitreal anti-vascular endothelial growth factor (VEGF) injections between April 2012 and August 2017. There were 101,932 procedures performed in 5890 patients. The two most common indications for injections were...
Bromfenac versus betamethasone in diabetic macular oedema
31 October 2023
| Kurt Spiteri Cornish
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Retina / Uvea / Vitreous
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Diabetic macular edema, betamethasone, bromfenac, central subfield thickness, intraocular pressure
This is a randomised, prospective, single-centre trial in patients diagnosed with diabetic macular oedema (DMO) with central subfield thickness (CST) of 250-500µm, who refused anti-VEGF treatment. Nineteen eyes of 19 patients were randomised to bromfenac (BF) or betamethasone (BM) drops,...
Fluorescein angiography and OCT in myopic CNV
1 December 2014
| Bheemanagouda Patil
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Retina / Uvea / Vitreous
Fluorescein angiography (FA) and spectral-domain optical coherence tomography (OCT) are the most common examinations used in the management of anti-VEGF therapy in choroidal neovascularisation (CNV). In comparison to FA, OCT provides a noninvasive evaluation of the macula. Myopic CNV are...