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603 results found

Choroidal vascularity in NAION

The authors present a cross-sectional, non-interventional study of healthy volunteers and those with non-arteritic anterior ischaemic optic neuropathy (NAION) recruited over a six-month period at a single site. NAION is the most common cause of acute optic neuropathy over the...

Do occult neuroretinitis and non-arteritic anterior ischaemic optic neuropathy differ in presentation?

This study evaluates differences between neuroretinitis and non-arteritic anterior ischaemic optic neuropathy (NAAION) in terms of patient demographics, clinical presentation, and optical coherence tomography (OCT) findings. Medical records of patients with a final diagnosis of occult neuroretinitis or NAAION were...

Apr/May 2014 Quiz 2

History A 29-year-old woman presented to the emergency department with a two week history of floaters and patchy peripheral visual field loss in the left eye (LE). She had no relevant medical history and she was not on any current...

Review of non-arteritic anterior ischaemic optic neuropathy

This article reviews the risk factors, clinical presentation and therapies that have been investigated for non-arteritic anterior ischaemic optic neuropathy (NAAION). Additionally, it provides an update from recent rodent and primate models, offering a new insight into the pathophysiology of...

Is there an association between dry eye disease and depression and anxiety?

Dry eye disease is a widespread ocular surface condition (prevalence 5.5-33.7%) that has been previously linked to systemic diseases, such as Sjogren, rheumatoid arthritis and more recently possibly also depression, in small population-based studies. The authors’ aim was to investigate...

Medical Ophthalmological Society Annual Meeting

By Muhammad Adil Seelarbokus, Final Year Medical Student, Newcastle University. With an ever-increasing ageing population with multiple co-morbidities presenting to clinics nowadays, the need for medical ophthalmologists is growing. The Medical Ophthalmological Society’s Annual Meeting seemed to be an excellent...

G-CSF intravitreal injections for NAION: a pilot study

In rodent models with anterior ischemic optic neuropathy (AION), granulocyte colony-stimulating factor (G-CSF) confers a neuroprotective effect on retinal ganglion cells (RGCs) via anti-apoptotic and anti-inflammatory processes. This prospective study investigated the efficacy of intravitreal injection of G-CSF for the...

What not to miss in neuro-ophthalmology Part 1

Neuro-ophthalmology is a complex and difficult subspecialty in ophthalmology. It has several connections to neurology, neuro-surgery, rheumatology as well as many other medical specialties. Working in an multidisciplinary team (MDT) environment is key to success in this subspecialty as mistakes...

Optic nerve swelling – your survival guide (part 1)

Assessment of optic nerve appearance and functions is a daily routine in neuro-ophthalmology. Following a recent high profile court case there has been a significant increase in the amount of referral to ophthalmology departments to assess the optic nerve and...

Serology testing in periocular inflammatory disease

This is a review article of serological tests in thyroid eye disease, IgG4-related disease and myasthenia gravis. The authors provide an overview of the current serology with a brief description of how they relate to the pathogenesis of each condition....

A review of the risk of nonarteritic anterior ischaemic optic neuropathy post-cataract surgery

A systematic review and meta-analysis are presented with the aim of assessing whether cataract surgery increases the risk of non-arteritic anterior ischaemic optic neuropathy (NAION) and identify potential predictors of risk. The search strategy components are outlined in detail. A...

A novel way to diagnose optic neuropathies using Bruch’s membrane opening

Differential diagnosis of optic neuropathies can be challenging but is crucial for the correct management of the underlying disease and prevention of further damage. Bruch’s membrane opening (BMO) was recently discovered as the anatomical border of the optic disc. BMO...