You searched for "carcinoma"
Staged excision of primary periocular BCC
2 December 2019
| Jonathan Chan
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Oculoplastics, Orbit
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eyelids, neoplasia, pathology, treatment surgery
This is a 10 retrospective review of case notes study of 437 patients of staged basal cell carcinoma (BCC) excisions between 2000 and 2017. All patients had 3mm clinically clear margins with staged excision and standard reconstruction techniques were performed...
Quiz Aug/Sep 2022
2 August 2022
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Ophthalmology
History A 58-year-old female patient was referred with a 2-year history, gradually enlarging, painless left upper lid lump. There was no bleeding or ulceration. She had no other eye symptoms and no other skin lesions. Her past medical history included:...
Take this waltz
My last weekend on-call was the busiest I can remember for a very long time. We were just completely swamped with patients. The weather was not too good that Saturday and it felt like every second inhabitant of our ocean...Outcomes of Hughes flap in lower eyelid reconstruction
1 April 2018
| Jaya Myneni
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Oculoplastics, Orbit
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Hughes flap, eyelid, surgery, tarsoconjunctival advancement flap
One hundred and 22 consecutive patients who underwent tarsoconjunctival advancement flap surgery for lower eyelid defects were part of this study. Ninety percent of them had lesion excision using Mohs micrographic surgery. Eighty percent of these were for basal cell...
Cancer associated retinopathy
Abdul Muhyemin Tarin reviews the presentation, pathophysiology and management of this paraneoplastic syndrome. Case presentation A 60-year-old hypermetropic female patient presented with several months’ history of painless blurred vision. Visual acuity (VA) was 6/24 and 6/9-1 in right and left...Oct/Nov 2019 Quiz
1 October 2019
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Ophthalmology
History A 62-year-old female patient was referred for rapid growth of a left periorbital soft tissue lesion with proptosis. Her past medical history included: hypertension, hyperlipidaemia and bipolar disorder. On examination: vision in the affected eye was hand movements, right...
The effect of everolimus on retinal pigment epithelium and proliferative vitreo-retinopathy
1 August 2018
| Kurt Spiteri Cornish
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Retina / Uvea / Vitreous
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Everolimus, mammalian target of rapamycin (mTOR), proliferative vitreoretinopathy, retinal detachment, ribosomal protein S6 (RPS6)
The principal cells involved in proliferative vitreo-retinopathy (PVR) are retinal pigment epithelial cells (RPE). Everolimus is a drug used in renal cell carcinoma which targets and inhibits a key regulatory protein in cancer (mTOR). In this study, the authors investigated...
Laissez-faire approach for medial canthus tumours
1 October 2017
| Jaya Myneni
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Ocular Pathology and Oncology
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Graft, laissez-faire, medial canthal defects
This is a retrospective comparative case series of patients who underwent reconstruction of a medial canthal defect using laissez-faire approach (LFS), or a full-thickness skin graft (FTSG). The surgical options were discussed with the patient and the treatment decision was...
Histopathology-guided management of ocular surface squamous neoplasia (OSSN) with corneal stromal or scleral invasion using ruthenium-106 plaque brachytherapy
11 January 2024
| Jonathan Chan
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Ocular Pathology and Oncology
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conjunctiva, eye (globe), pathology, salivary gland
This is a retrospective interventional consecutive case series of 42 eyes of 42 patients with OSSN with histopathologically proven corneal stromal and / or scleral invasion following excision biopsy. The mean tumour basal diameter was 9.3mm and thickness of 3.1mm...
A case report of papilloedema caused by unilateral jugular vein thrombosis
1 February 2016
| Claire Howard
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Headache, idiopathic intracranial hypertension, jugular vein thrombosis, papilloedema
In rare cases, unilateral jugular vein thrombosis can lead to increased intracranial pressure and papilloedema, resulting in headaches and visual loss. The authors describe the case of a 45-year-old patient with squamous cell carcinoma of the larynx who developed right...
Dec/Jan 2019 Quiz
1 December 2018
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AMD, Emergency Ophthalmology, Genetics, Ophthalmology, Optometry, EYE - Cataract, EYE - Cornea, EYE - Glaucoma, EYE - Neuro-ophthalmology, EYE - Imaging, EYE - Oculoplastic, EYE - Oncology, EYE - Orbit, EYE - Paediatrics, EYE - Pathology, EYE - Refractive, EYE - Strabismus, EYE - Vitreo-Retinal
History A 72-year-old male presented to his GP with a large ulcerated lesion on his right lower eyelid present for six months and enlarging in size. He had an urgent referral to a tertiary centre for specialised examination. The lesion...
Atopic keratoconjunctivitis (AKC) and ocular surface squamous neoplasia (OSSN)
1 April 2017
| Yamini Krishna
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Ocular Pathology and Oncology
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Atopia, Inflammation, Masquerade, Neoplasia, Ocular surface
The authors present two cases of invasive OSSN in patients with severe AKC. Case 1 was a 73-year-old male with severe AKC and atopic eczema who developed a suspicious papillary-like limbal lesion in the left eye. He had an excisional...