You searched for "fluorescein"
OCTA and pigment epithelium detachments
1 December 2018
| Saruban Pasu
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EYE - Vitreo-Retinal
Yannuzzi et al. report on their study aiming to evaluate the ability of optical coherence tomography angiography (OCTA) to differentiate vascularised from nonvascularised pigment epithelium detachments (PEDs) using conventional imaging techniques, including fundus fluorescein angiography (FFA) and indocyanine green (ICG),...
Dacryocystosclerotherapy as an alternative to dacryocystectomy
In this article, the authors evaluate the role of sclerosing agents in dacryocystosclerotherapy (DCST) and aim to see whether it is an alternative to dacryocystectomy (DCT) in a specific group of patients. Thirteen lacrimal drainage systems of 10 patients with...Diabetic Macular Oedema
1 December 2013
| Pouya Alaghband
Diabetes mellitus is a metabolic disorder that affects the metabolism of all three categories of carbohydrates, lipids and proteins. This condition is characterised by chronic hyperglycaemia [1]. This can cause end organ damage. The estimated worldwide diabetes prevalence for 2010...
RaScaL Study
1 June 2015
| Sofia Rokerya
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Retina / Uvea / Vitreous
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Diabetic macular edema, Fluorescein angiography, Anti-VEGF, Ranibizumab, Laser photocoagulation, Combination therapy, Optical coherence tomography
The RaScaL study was a six month, single-centre, controlled, prospective phase I/II study in which subjects with diabetic macular oedema (DME) and associated peripheral nonperfusion on ultrawide-field fluorescein angiography (UWFA) were randomised to: (1) study arm: ranibizumab (0.5 mg) injection...
Handbook of Retinal OCT
This is not a large colour atlas for optical coherence tomography (OCT) with comprehensive reference lists offering an in-depth description of this popular technology, but an up-to-date pocket or handbag-sized, soft-backed textbook that is likely to become a well-thumbed primer...Glucose-sensing contact lenses replace the finger prick test!
Simerdip Kaur takes a look at the latest ophthalmology-related news stories and asks which are scientific reality and which are ‘fake news’. Headline: Glucose-sensing contact lenses replace the finger prick test! The concept of contact lenses was first illustrated by...
Atlas of Wide-Field Retinal Angiography and Imaging
Through extensive illustrations, this book, comprehensively yet concisely, covers the diagnostic speciality of wide-field retinal angiography and imaging. There are 15 chapters with contributions from 29 leading experts in this particular field who are mainly based in the USA, but...
Assessment and management of dry eye disease
This paper is an update on the assessment and management of dry eye disease (DED). According to the second International Dry Eye Workshop 2017, “Dry eye is a multifactorial disease of the ocular surface characterised by a loss of homoeostasis...
Rebamipide 2% for dry eye
Rebamipide is a quinolinone derivative that has been found to increase mucin production and the number of conjunctival goblet cells. A previous phase two study has shown rebamipide 2% to be better than placebo in improving the ocular surface and...Pigmented paravenous retinochoroidal atrophy
4 December 2024
| William Spackman, Tun Giap Tan, Stephen Turner
|
EYE - Imaging, EYE - Vitreo-Retinal
Presentation A 46-year-old Caucasian female was referred to the eye clinic by her local optician following a routine sight test. She was noted to have pigmentary retinal changes in both eyes but was asymptomatic with no visual complaints. At presentation...
Therapy for limbal stem cell deficiency: cell fate after limbal stem cell transplants
1 October 2014
| Aws Al-Hity, Sanjay Mantry, Ken Lai, K Ramaesh
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EYE - Cornea
“The beauty of scientific research lies in that the search for answers often yields yet more questions.” A large body of evidence points to the corneoscleral limbal location as the repository of putative epithelial stem cells [1]. Thoft proposed the...
New mouse model of diabetes mellitus
1 April 2014
| Graham Wallace
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Retina / Uvea / Vitreous
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aldose reductase, cell signaling P-ERK1/2, P-SAPK/JNK, P-Akt, diabetic rats, diabetic retinopathy, green fluorescent proteins, growth factors VEGF, bFGF, TGF-β, retinal vascular changes, transgenic diabetic mouse models
Diabetic retinopathy (DR) is a serious complication of diabetes. It is driven by the loss of pericytes, cells which control vascular function, due to excess formation of sugar alcohols by the enzyme aldose reductase (AR). AR has been shown to...
