You searched for "immunosuppression"
White dot syndromes
1 September 2015
| Gwyn Samuel Williams
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EYE - Vitreo-Retinal
It is fair to say that trainees and consultants who are not medical retina specialists are a bit scared of the so called retinal ‘white dot syndromes’. It is easy to understand why this is the case, as almost every...
Atopic keratoconjunctivitis (AKC) and ocular surface squamous neoplasia (OSSN)
1 April 2017
| Yamini Krishna
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EYE - Pathology, EYE - Oncology
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Atopia, Inflammation, Masquerade, Neoplasia, Ocular surface
The authors present two cases of invasive OSSN in patients with severe AKC. Case 1 was a 73-year-old male with severe AKC and atopic eczema who developed a suspicious papillary-like limbal lesion in the left eye. He had an excisional...
Incidence of ocular myasthenia gravis and risk factors for conversion to generalised disease
This population based retrospective cohort study evaluates the incidence of ocular myasthenia gravis (OMG) as well as risk factors for transformation to generalised myasthenia gravis (GMG). Sixty-five patients (40 male and 25 female) with newly diagnosed with myasthenia gravis (MG)...
RPE use similar pathway to regulatory T cells to inhibit immune response
Retinal pigment epithelial (RPE) cells form an important part of the blood-retinal barrier that protects the neuronal cells responsible for sight. RPE cells are involved in innate and adaptive immune responses via expression of surface molecules and release of cytokines....
Uveitis Second Edition
1 October 2014
| Sofia Rokerya
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EYE - Vitreo-Retinal
This book is a comprehensive source of information on the subject of uveitis. The target audience includes ophthalmologists, allied health professionals with special interest in this area and general physicians treating patients with multisystem inflammatory disease with involvement of the...
Differential diagnosis of inflammatory optic neuritis
1 February 2014
| Claire Howard
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EYE - Neuro-ophthalmology
The authors present the differential diagnosis of inflammatory optic neuritis (ON) to include multiple sclerosis, infectious optic neuritis, systemic disease and neuromyelitis optica (NMO). The features of ON for the varying aetiologies are detailed including incidence and overlap. In acute...
Herpes zoster ophthalmicus: a clinician’s perspective
25 January 2023
| Anitha Priya Arun Shankar, A. R. Reddy
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EYE - General
Introduction Herpes zoster, commonly known as shingles, is caused by the reactivation of varicella zoster virus (VZV). The term herpes is derived from a Greek work, herpein, which means ‘creeping’ and the word zoster means a belt or a girdle...
A complicated case of cytomegalovirus viremia: “What would you do doctor?”
1 February 2016
| Salman Waqar, Vasant Raman, Thomas Cudrnak
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EYE - Vitreo-Retinal
Mrs W walked gracefully into my urgent care clinic. It was another busy session and I hoped she did not have anything serious going on which might slow the clinic further. She was an elegant 72-year-old lady who seemed like...
Behind the eyes: Unravelling the mystery of a painless progressive proptosis
Orbital fungal infections have the potential to give rise to serious complications. While these infections typically originate in the sinuses, patients may initially exhibit ocular symptoms. As a result of the diverse and often vague clinical manifestations (especially during the...Ocular mucous membrane pemphigoid: the importance of early detection and treatment
1 August 2014
| Inderpaul S Sian, Bhaskar Gupta, David Cadman, Keith Bates
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EYE - Oculoplastic, EYE - Orbit
Mucous membrane pemphigoid (MMP) is an autoimmune blistering disorder that is characterised by subepithelial bullae. The ocular manifestation of MMP, ocular mucous membrane pemphigoid (OMMP), is a sight-threatening condition characterised by conjunctival cicatricial changes associated with corneal vascularisation and scarring....
IVTA use in Behçet’s disease
This study aimed to evaluate the efficacy and safety of intravitreal triamcinolone acetonide (IVTA) injection (4mg/0.1ml) in controlling posterior segment inflammation in patients with Behçet’s disease. Medical records of consecutive patients diagnosed with Behçet’s who underwent IVTA between July 2005...
Methotrexate and mycophenolate mofetil for non-infectious uveitis
1 February 2015
| Brian Ang
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Retina / Uvea / Vitreous
This is the first reported randomised clinical trial comparing methotrexate versus mycophenolate mofetil (MMF) for the treatment of non-infectious intermediate uveitis, posterior uveitis or panuveitis. To be eligible for recruitment, patients had to be on ≥15mg oral prednisone and demonstrated...
