You searched for "neovascular"
Inflammation and microvascular changes in diabetic retinopathy
1 February 2022
| Kurt Spiteri Cornish
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Retina / Uvea / Vitreous
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Aqueous flare, diabetes mellitus, diabetic retinal neuropathy, diabetic retinopathy, intraocular inflammation, neuroinflammation
Studies have shown that neurodegeneration and inflammation in the retina start early in diabetic retinopathy (DR) and can be present before the latter is clinically evident. The aim of this retrospective review of 99 diabetic patients was to evaluate retinal...
Atrophy and anti-VEGF
1 August 2019
| Saruban Pasu
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Retina / Uvea / Vitreous
The aim of this study was to investigate treatment factors, along with ocular and systemic factors for their association with macular atrophy (MA) incidence in eyes with neovascular age-related macular degeneration (nAMD) treated with anti-VEGF aflibercept or ranibizumab according to...
OCTA in angioid streaks
1 February 2019
| Saruban Pasu
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Retina / Uvea / Vitreous
This paper reports on the optical coherence tomography angiography (OCTA) features of choroidal neovascularisation (CNV) secondary to angioid streaks and the ability to predict CNV activity. A total of 38 eyes of 19 patients were included in the study. Thirty...
Shifting the paradigm of managing patients in medical retina: how real-world data can help us to improve clinical practice
1 February 2015
| Pearse A Keane (Prof), Adnan Tufail
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Retina / Uvea / Vitreous
The ophthalmic subspecialty of ‘medical retina’ has undergone dramatic changes in recent years. With the introduction of ranibizumab (Lucentis, Novartis), a specialty formerly dominated by laser-based therapies has been transformed to become, in large part, pharmacotherapy-based. To date, these pharmacotherapies...
What’s new in wet AMD papers?
1 December 2016
| Rod McNeil
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Retina / Uvea / Vitreous
Paper presentations on neovascular (‘wet’) age-related macular degeneration (AMD) from the 16th European Society of Retina Specialists Congress, Copenhagen, September 2016, outline recent research directions evaluating the impact of vision loss on key health domains, patient preferences in the process...
Diagnosis and management of orbital vascular malformations
This is an authoritative review of a controversial and difficult clinical area. The authors have experience of over 350 cases and provide a well-structured review of the classification and management of orbital vascular malformations. They emphasise the need to understand...Do bilateral same day intravitreal injections increase the risk of endophthalmitis?
1 February 2019
| Tasmin Berman
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Retina / Uvea / Vitreous
This large retrospective cohort study reviewed all patients who had bilateral intravitreal anti-vascular endothelial growth factor (VEGF) injections between April 2012 and August 2017. There were 101,932 procedures performed in 5890 patients. The two most common indications for injections were...
Hyphema after trabeculectomy with MMC
1 October 2014
| Lorraine North
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Glaucoma
The authors retrospectively reviewed the medical records of consecutive patients with glaucoma who underwent trabeculectomy with mitomycin C between June 2005 and December 2010 to determine the risk factors for hyphema after surgery. Of the 420 patients, 104 (24.8%) had...
Anatomical and functional outcomes following switching from aflibercept to ranibizumab in NARMD
5 June 2020
| Jonathan Chan
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Retina / Uvea / Vitreous
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clinical trial, degeneration, imaging, macula, neovascularisation
This is a six-month, prospective, single-arm study in the UK and Germany. A total of 100 patients were enrolled (one in the primary failure group, 99 in the suboptimal treatment response group), treated three-monthly intravitreal ranibizumab injections (0.5mg), and then...
Vision loss during Eylea treatment for AMD
1 December 2017
| Saruban Pasu
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Retina / Uvea / Vitreous
This report investigated patients who lost more than two lines of vision despite periodic injections of aflibercept and explored the factors associated with vision loss. One hundred and ninety-six eyes were included in this study over a two year period....
Submacular haemorrhage associated with nAMD: A meta-analysis and meta-regression on use of tPA and anti-VEGFs
1 November 2024
| Sofia Rokerya
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EYE - Vitreo-Retinal
The aim of this study was to evaluate the efficacy of a combination of tPA and anti-VEGF in the treatment of submacular haemorrhage (SMH) associated with neovascular age-related macular degeneration (nAMD). A systematic review meta-analysis following PRISMA guidelines, focusing on...
Update: Non-infectious retinal vasculitis
2 December 2024
| Sofia Rokerya
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EYE - Vitreo-Retinal
This review article summarises the update on non-infectious retinal vasculitis (RV). It is primarily classified based on the type of retinal vessels involved and further sub-classified as occlusive or nonocclusive. Clinically it can occur as an isolated ocular entity or...