You searched for "tumour"
Pituitary tumours: why are they so often missed?
1 August 2017
| James F (Barry) Cullen
|
EYE - Neuro-ophthalmology
Part 2: Clinical varieties, anatomical considerations and case report (see also Part 1 and Part 3) For ophthalmologists there are four types of pituitary tumour to be considered, three of which are named according to the hormone secreted, along with...
Nanoparticle administration of latanoprost
1 December 2013
| Graham Wallace
|
Glaucoma
Glaucoma is a progressive optic neuropathy characterised by increased ocular pressure and loss of retinal ganglion cells. Conventional drug therapy with eye drops to reduce intraocular pressure (IOP) has variable bioavailability and can lead to ocular surface disease. In this...
Epidemiology of ocular cancer in Cali
The aim of this study was to describe the population trends of incidence and survival rates of ocular cancer in Cali, Columbia. Data was retrieved from the Registro Poblacion de Cancer de Cali (RPCC, i.e. Population Cancer Registry of Cali)...Suspected vitreous seeding of uveal melanoma
This is a retrospective non-randomised study of 23 patients with consecutive uveal melanoma who underwent diagnostic vitrectomy between the period of January 2000 and November 2013. The reason for vitrectomy was suspected dissemination of tumour cells inside the eye. The...PD-1 and PD-L1 in exenteration specimens
This is an immunohistochemical study looking at variation in the expression of the programmed death-1 receptor (PD-1) and the programmed cell death ligand-1 (PD-L1), comparing cutaneous malignancies which invaded the orbit with uncomplicated nodular basal cell carcinomas. The authors retrospectively...Imaging and histological relationship of orbital Schwannomas
This is a retrospective review of 15 patients with orbital Schwannomas comparing the radiological characteristics, in particular the signal intensity on MRI, with the histological sub-types of the tumours. Five patients had MRI imaging alone, three had CT alone and...Uveal melanoma
3 August 2023
| Mertcan Sevgi, Timothy Beckman, Paul Cauchi, Julie Connolly, Vikas Chadha
|
EYE - Pathology, EYE - Oncology, EYE - Imaging
Uveal melanoma is the most common primary intraocular tumour. However, they are still rare, with an incidence of 2-8 per million [1]. The presence of a choroidal naevus is a risk factor for uveal melanoma [1]. Patients with choroidal lesions...
Portable vision reading device shows promise for low vision after brain injury
2 August 2024
| Claire Howard
|
Neuro-Ophthalmology
The authors report a small sample cohort study evaluating the impact of a portable vision reading device (OrCam Read) on vision-related quality-of-life and independent functional status in patients with low vision due to stroke or brain tumours. Six patients with...
Brimonidine day and night time IOP
1 October 2014
| Lorraine North
|
Glaucoma
|
brimonidine, aqueous humor dynamics, intraocular pressure, ocular hypertension
The authors describe a randomised double masked study of 29 participants with ocular hypertension (OHT) who either self-administered 0.2% brimonidine or placebo three times daily for six weeks. Patients were seen during day time and night time visits and had...
Enzymatic clearance of anterior chamber infiltrate in uveitis
1 February 2014
| Graham Wallace
|
Retina / Uvea / Vitreous
|
aqueous humor, endotoxin-induced uveitis, lipid metabolism, phospholipase A2, uveitis
Aqueous humour (AH) which fills the anterior chamber (AC) of the eye provides nutrients to the cornea and the lens. Clearance of cellular and particular matter from AH is necessary for good visual acuity. In part this is achieved by...
A prospective trial of adjuvant therapy for high-risk melanoma
5 June 2020
| Jonathan Chan
|
Ocular Pathology and Oncology
|
adjuvant therapy, metastasis, uveal melanoma
Patients diagnosed with iris, ciliary body or choroidal melanoma of high-risk tumour cytogenetics (monosomy 3>/= 20% of cells), were treated with adjuvant low-dose dacarbacine (DTIC) and interferon –alpha-2b (IFNA-2b), following primary treatment (enucleation, brachytherapy or resection). DTIC was given intravenously...
Outcomes of plaque radiotherapy for retinoblastoma
3 April 2023
| Fiona Rowe (Prof)
|
Paediatric Ophthalmology / Strabismus
The study authors evaluate their experience of plaque radiotherapy for retinoblastoma (RB) in 41 eyes of 41 patients that failed intra-arterial chemotherapy (IAC). This was a retrospective review including 21 females and 20 males. Median age was 18 months and...