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Ranibizumab safety in pregnancy

Vascular endothelial growth factor (VEGF) plays a pivotal role during pregnancy, and systemic anti-VEGF administration during this period should thus be avoided. VEGF is expressed in multiple embryonic and foetal tissues during development, with the highest levels found in the...

Cataract surgery in small adult eyes

This is a retrospective audit of a five year study period, between the periods of January 2006 to December 2010, where a surgical log book search was performed. The inclusion criteria of this study were intraocular lenses (IOL) power greater...

Cystoid macular oedema following cataract surgery

This review covers the history, incidence, diagnosis, risk factors, pathophysiology and medical management of postoperative macular oedema (PCMO), with a particular emphasis on key contemporary studies and novel observations. The authors revisit the incidence of well-established risk factors including intraoperative...

IOL tilt with air tamponade vs. salt solution

In this study the authors made a comparison of significant postoperative tilt of IOL with air tamponade as opposed to balanced salt solution, in the procedure of combined phaco with IOL and vitrectomy. Thirty-four patients were included into the analysis....

Caffeine concentration in the vitreous after drinking coffee

Caffeine is known to penetrate many bodily fluids, including the vitreous. In this prospective study, investigators measured caffeine levels in vitreous samples from patients undergoing vitrectomy and epiretinal membrane peel. Patients were divided into habitual and non-habitual coffee drinkers. One...

Retinal traction during ERM peeling

This prospective study aimed to quantify the retinal thickening induced by epiretinal membrane (ERM) peeling and to correlate this thickening with postoperative retinal function. Twenty-five patients who required surgery for idiopathic ERM were included in the study. The authors performed...

Safety and outcome of microincision vitreous surgery in uveitis

This paper reports the outcomes of microincision vitreous surgery (MIVS) 23G/25G in uveitis of 103 patients (106 eyes) who underwent diagnostic MIVS over a period of four years at the Advanced Eye centre in Chandigarth India. The postoperative evaluation included...

Full thickness macular hole after YAG PI

The authors report a case of macular hole post YAG peripheral iridotomy (PI) of a patient with pre-existing vitreomacular adhesion. Although a relatively safe procedure, some anterior segment complications are well documented such as corneal endothelium damage, rise in IOP,...

Quiz Dec/Jan 2020

History A 69-year-old female patient was referred to the uveitis clinic from her local district general hospital with a left posterior uveitis which had been unresponsive to high dose steroids. She had no other previous ophthalmic history nor significant systems...

Aug/Sep 2015 Quiz 2

History A two-year-old female child presented with loss of vision in her left eye. Examination showed leukocoria and intraocular calcification was identified on scanning. The suspected diagnosis was intraocular retinoblastoma and the child underwent an enucleation. The eyeball was submitted...

Oct/Nov 2014 Quiz

History 12-year-old cattle herder in Bangladesh. Loss of vision right eye – over 2/12 to no perception of light (NPL). B-scan showed choroidal thickening. Suspected to be choroidal ‘tumour’. Enucleated. Figure 1. Figure 2. Figure 3. Figure 4. Figure 5....

In conversation with Robert MacLaren

Professor Robert MacLaren gave the Keeler Lecture at the Royal College of Ophthalmologists Annual Meeting in May 2019 on gene therapy for retinitis pigmentosa. We caught up with him afterwards to find out more. What are the key messages of...