You searched for "neuropathy"

621 results found

Laser photocoagulation vs. intravitreal (IVT) aflibercept for ROP

The efficacy, recurrence rate and requirement for additional treatment were compared between laser photocoagulation and IVT of 1mg/0.025ml aflibercept in the treatment of retinopathy of prematurity (ROP). The study included 27 babies (51 eyes) who completed a follow-up period after...

ROPScore for detection of any and severe ROP

ROPScore is a free tool consisting of a logistic regression equation to calculate the risk per child and calculated one time per infant at six weeks of life. It helps to predict severe retinopathy of prematurity (ROP). This study aimed...

Cystoid macular oedema following retinal detachment surgery

There are limited studies examining the incidence and risk factors for postoperative cystoid macular oedema (CMO) following rhegmatogenous retinal detachment (RRD) repair. Postoperative CMO is thought to be due to pro-inflammatory state, where numerous cytokines lead to tight junction dysfunction,...

Chorioretinal atrophy in punctate inner choroidopathy / multifocal choroiditis

This study reported the five-year outcomes of chorioretinal atrophy (CRA) progression in patients with punctate inner choroidopathy (PIC) or multifocal choroiditis (MFC) in 45 eyes of 36 patients. The mean age of the cohort of patients was 37 ±13.37 years...

Preterm birth and refractive error in an Indian infant population

This study was undertaken to identify and compare the changes in refractive outcome in infants with and without retinopathy of prematurity (ROP), to inform incidence of refractive error. This was a prospective study of 300 consecutive premature infants with birth...

Pathophysiology of diabetic macular oedema: why combination therapy may be better

The prevalence of diabetes has continued to increase over the years. It is currently estimated that there are 382 million with diabetes worldwide in 2013, and that this figure is expected to rise to 592 million by 2035 [1]. In...

Visual acuity outcomes after cataract surgery in type 2 diabetes (NIDDM): the action to control cardiovascular risk in diabetes (ACCORD) study

This is a retrospective case-control study of 1136 eyes enrolled in the 784 ACCORD patients receiving cataract surgery between 2001-2014. 362 / 1136 eyes had gradable fundus photography for diabetic retinopathy (DR). Seven hundred and sixty-two eyes (67.1%) achieved 20...

Retinal changes prior to hydroxychloroquine toxicity

In this retrospective longitudinal study, the authors examined changes in retinal layer thickness in patients taking hydroxychloroquine without evidence of retinopathy. Patients were drawn from a hydroxychloroquine screening clinic and required at least two OCT scans, at least one year...

A case report showing the natural history of papilloedema

The case report describes a 54-year-old woman who developed increased intracranial hypertension due to chronic dural venous sinus thrombosis in the absence of any significant comorbidity. In the years preceding diagnosis, the patient underwent routine diabetic retinopathy screening; however, gradual...

FA findings in treatment-naive premature infants

This retrospective study examined fluorescein angiography (FA) images of 162 eyes of 81 treatment-naive infants with retinal vascular immaturity and persistent avascular retina (PAR) despite exceeding postmenstrual age of 60 weeks. Disc diameter (DD), optic disc-to-fovea distance (FD), the length...

The effect of everolimus on retinal pigment epithelium and proliferative vitreo-retinopathy

The principal cells involved in proliferative vitreo-retinopathy (PVR) are retinal pigment epithelial cells (RPE). Everolimus is a drug used in renal cell carcinoma which targets and inhibits a key regulatory protein in cancer (mTOR). In this study, the authors investigated...

ANGPTL-4 inhibition reduces inflammation in diabetic retinopathy

Diabetic retinopathy (DR) is the most common cause of blindness in working-age humans, and numbers are rising due to increased cases of type 2 diabetes (T2D). T2D is associated with increased obesity and dyslipidaemia, which is a major risk factor...