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Doctor by the sea (Pete’s Hidden Curriculum Part 1)
See Pete's Hidden Curriculum Part 2 here. “They can always hurt you more.” This is The Fat Man’s Law Number 8 from the book The House of God by Samuel Shem. For those that have not read this book, it...
Features of AMD treatment non-responders
This is a retrospective consecutive case series of 365 eyes with age-related macular degeneration (AMD) who had three monthly intravitreal aflibercept treatments for at least 12 months. Responders were defined as complete resolution of exudation, intraretinal oedema, subretinal fluid, pigment...
Surgical treatment for monocular elevation deficit
Type 1 monocular elevation deficiency is a restrictive form identified by positive results on forced duction testing in elevation, normal elevation forced generation test, elevation of saccadic velocity and absence of poor Bell’s phenomenon. The authors aimed to evaluate the...
Surgery for third nerve palsy (2019)
The authors present a new technique for split muscle medial transposition surgery of the lateral rectus plus union with the distal split stump of the medial rectus. This increases the length of the contracted lateral rectus through the addition of...
Using small amplitude saccades to assess saccadic velocity
Saccades are a key component in the assessment and diagnosis of neuro-ophthalmological disorders. Clinicians are typically taught to use large amplitude saccades (LAS) of at least 20 degrees to assess saccadic velocity. It has been suggested, however, that small amplitude...
Topical nonsteroidal ant-inflammatory drugs (NSAIDs) in patients undergoing cataract surgery
Inflammation is a major risk factor for the development of cystoid macular oedema (CMO) after cataract surgery, leading to breakdown of the blood-retina barrier. There is a correlation between severity of CMO and level of postoperative inflammation. Laser flare meter...
Efficacy of cyclo 1% spray
The aim of this study was to evaluate the efficacy and tolerability of cyclopentolate 1% spray in patients aged three to six years. This was a cross section parallel group study of 61 children. Thirty-one received cyclo 1% drops and...
Treatment of Sjogren’s Syndrome dry eye in mouse model
Sjogren’s syndrome (SS) is a chronic autoimmune disease characterised by inflammation of the exocrine glands, specifically the salivary and lacrimal glands that produce saliva and tears, respectively. The immune-mediated attack on the salivary and lacrimal glands leads to the development...
Effective contrast ratio as a measure of binocular visual perception
The authors used a binocular phase combination paradigm to quantitatively evaluate and compare the binocular visual perception of normal individuals and patients with different types of strabismus to understand the binocular visual perception of patients with strabismus and evaluate whether...
How to achieve 1% solution of Lissamine green
Lissamine green (LG) concentration of 1% is clinically effective in the diagnosis of ocular surface disease. LG is now commercially available only in a form of dye-impregnated strips, whose concentration is insufficient. This study examined how to achieve 1% concentration...
Differential inhibition of EAU by CTLA4 and IL-6
Cytotoxic T lymphocyte antigen-4 (CTLA4) binds both CD80 and Cd86 and inhibits T lymphocyte activation via CD28. Il-6 is a pleiotropic cytokine that has been associated with many autoimmune conditions including uveitis. Blockade of these molecules by either CTLA4-Ig, a...
